Abstract
Overview
Introduction
Advanced heart failure is a growing issue. Existing pharmacological strategies
increase the survival rates of acute heart failure patients, providing a
growing source of patients with advanced disease. In view of long waiting
lists for heart transplantation and the growing lack of donors, cardiac
resynchronization and mechanical circulatory support devices have demonstrated
promising results.
Scope
- What are the current definitions, diagnostic methods and treatment
approaches of the early stages of the disease?
- What are the main issues surrounding treatment approaches in the advanced
stages of the disease?
- What is the current role of cardiac resynchronization therapy in treatment
of advanced heart failure?
- What are the main non-pharmacological options as alternatives to heart
transplantation in advanced heart failure?
Report Highlights
With no new drug therapies addressing advanced heart failure and existing
pharmacological strategies failing to compensate a weakening heart,
alternative, non-pharmacological solutions have to be found. In view of long
waiting lists for heart transplantation and the growing shortage of donor
hearts, the focus of treatment must shift onto devices.
Ventricular dyssynchrony is a well recognized problem in advanced stages of
heart failure. Clinical trials investigating ventricular dyssynchrony cardiac
resynchronization have demonstrated promising results. However, this
technology provides only temporary, symptomatic relief and neither cures nor
fully stops the progression of the disease.
In light of the growing shortage of donor hearts and failing pharmacological
strategies, an artificial mechanical heart has been a long sought-after
technology. Although the developments started decades ago, a fully implantable
total artificial heart is still at the concept stage, with many years of
research and development yet to come.
Reasons to Purchase
- Understand current definitions, diagnostic methods and treatment
approaches in advanced heart failure
- Current dynamics and future trends of the technology developments treating
advanced heart failure
- Major technological and industry issues surrounding technological progress
and new product development
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