Abstract
Breast cancer is a complex heterogeneous disease characterized by uncontrolled
growth and spread of abnormal cells. It is also very prevalent, with reports
from the World Health Organization estimating that more than 1.2 million
people will be diagnosed with breast cancer in 2005, worldwide. In the United
States, breast cancer is the second most common cancer in women (following
skin cancer) with 212,930 new cases estimated for 2004 and an associated
40,840 deaths. In Europe, approximately 200,000 women are diagnosed with
breast cancer each year (41,000 in the UK). Consequently, breast cancer is a
high-priority research area and is recognized as one of the most aggressively
pursued diseases in the history of medicine.
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