Impact of Nano Materials in Drug Delivery & Human Tissue Engineering

Table of Contents

Chapter 1: Executive Summary

Chapter 2: Nanomaterials Relating to the Drug Discovery, Drug Delivery & Tissue Engineering Industries

• Nanoparticles
  • Quantum Dots (QDs)
  • Gold Colloids
  • Gold & Quantum Dots for Molecular Diagnostics
  • Magnetic Nanoparticles
  • Dendrimers
  • Nanoshells
  • Carbon Nanotubes & Nanotube Matrices
  • Multiplex Molecular Tagging with QDs, Nanotags, and Nanoprisms
  • Nanobarcodes
  • Biobarcode Assay for Proteins
  • Nanoparticle-based Colorimetric DNA Detection Method
  • Liposomes
  • Multilayered Nanoparticles
• New MRI Nanomaterials as Probes for Imaging Agents-Gadolinium in Fullerenes & Quantum Dots
  • Molecular Imaging
• Drug Delivery and Therapeutics-Bioavailability through Nanocrystals
  • Rexin G-An FDA Approved Targeted Delivery System (TDS)
  • Nanocrystals in Immunohistochemistry & Nanomedicine
  • Fullerenes for Delivering Therapeutic Molecules
  • Injectable & Topical Platforms Enhanced by Nanoparticluate Technologies
  • Nanotechnologies with Biochips & Protein chips
• Nano Biosensors
  • Nanowire Biosensors using Boron-doped Silicon Nanowire
  • Viral Nanosensor
  • Probes Encapsulated by Biologically Localized Embedding Nanosensors
  • New Nano-based Biosensor Technologies in Market
• Nano Tissue Engineering-Nanophase Biomaterials
  • Biocompatible Polymer Nanofibers
• Nanochemicals Against Cancer
  • Nanodrugs and Companies Targeting Cancer
• Nanobiotechnology' s Contributions to the Pharmaceutical/Medical Sectors

Chapter 3: Commercial Pharmaceutical & Tissue Engineering Product Applications Using Nano Materials

• Nano Technology and the Pharmaceutical/Tissue Engineering
• Product Applications Market in 2005
• Nanoengineering and Emerging Nanotechnology
  • Nanoparticles
  • Carbon Nanoparticles and Nanotubes Market
• Medical & Healthcare Diagnostic Devices Markets
  • Reporter Molecules and Molecular Tags for Biomolecular Detection
  • Biosensors
  • Contrast and Imaging Agents for MRI and PET
• Nanobiotechnology Utility in the Drug Discovery and Delivery Process
  • Solubilizing Pre-existing Drugs and Enhancing Controlled Drug Delivery
  • Improved Drug Formulations
  • Controlled Released Drugs
  • Multifunctional Drug Delivery Platforms
  • Targeted Drug Delivery Platforms
  • Targeted Drug Delivery
  • Devices for Targeted Drug Delivery
• Medical & Tissue Engineering Nano Material-based Products in 2005
  • Wound Dressings and Wound Repair
  • Stents and Catheters
  • Implants and Prosthetics
• Future Markets of Pharmaceutical and Medical
• "Nano Material-based" Products
  • Ongoing Clinical Trials using Nano material-based drugs
  • National Nanotechnology Advisory Panel Evaluation of the US Nano
  • Sector Markets

Chapter 4: Health, Environmental, and Societal Impacts of Nanoparticles

• Free Nanoparticles
  • Free Nanoparticle Safety Needs To Be Assessed
  • Potential Exposure Routes
  • Nanoparticles Can Be Toxic by Inhalation or through Skin Exposure
  • Factors Affecting Deleterious Effects of Nanomaterials
  • Eco-toxicity-On the Environment and on Other Species
  • Possible Adverse Health Issues
• Regulatory Issues of Nanotechnology
  • Royal Society & Royal Academy of Engineering July 2004 UK Report
  • The US FDA
• Future Considerations
• Social Science Issues
  • Societal Impacts
  • Personal Safety versus Covert Surveillance
  • Is the Science Fiction Larger than the Science of Nanotechnology?

Chapter 5: Global Investments by Private and Federal Resources

• Private Funding Accounts for Almost 40-50 % of Investment in the Nanotechnology Sector
• Global Distribution of Funding Sources of Nanotechnology
• Private Venture Capital Funding in the US Market
• Similarities between Nanotechnology, Semiconductor Industry, and DNA Technologies
• Patents as Indicators of the Maturity of Nanotech Investments
  • Big Pharma' s Stumbling Block-dying Patents
  • Global Distribution of Patents and Academic Publications in Nano Areas-
  • The Rise of China
• World Leaders in Nano Investment-US, Japan, EU & China
  • United States has invested $4.7 Billion Since 2001
  • Japan Spent $800 Million for Nanobiotechnology In 2005
  • China will have Invested $600 Million by 2007
  • Investments by Other Asian Countries
  • $1 Billion from Germany, France UK & Sweden
• Nanotechnology Global Investment was Approximately $9 Billion in 2005

Chapter 6: Nanobiotechnology Companies

• Nano Material Manufacturing Companies to Watch
  • Dendrimer, Fullerene & Nanotube-based Companies
  • Nano Arrays & Molecular Tag Companies
• List of Nanobiotechnological Companies

Chapter 7: Company Profiles