Abstract
Introduction
Pharmacogenomics will revolutionize the drug industry by linking the right
drug to the right patient. Several companies and regulatory agencies are
leading the charge to implement this approach of developing targeted
medicines. PGx's integration is inevitable; pharma companies must get on board
now or risk being left behind.
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Big pharma companies have become increasingly interested in PGx. These
companies realize that PGx offers a way to develop better and safer drugs.
Which companies are leading the charge to integrate PGx into drug discovery
and development? Appropriate genetic markers and well-documented patient
samples are critical to determining disease correlations. How are companies
obtaining this information, and how are they using it to create personalized
medicines? Although PGx is being integrated into many aspects of drug
discovery and development, many regulatory and ethical challenges persist.
What are the major issues remaining, and what are companies and regulatory
agencies doing to overcome these challenges?