Abstract
"Risperidone' s U.S. patent will expire in 2007, changing the landscape for all
atypical antipsychotics as cost becomes a prescribing and reimbursement
factor. Competitors will best preserve revenue streams by gaining approval for
new indications. Bipolar depression is among the most promising additional
labels that companies are pursuing."- Lulu Pickering, Ph.D., Program
Manager
Introduction
The $15 billion antipsychotics market will be hard hit by generics of nearly
all the most frequently prescribed atypicals and by a dearth of breakthrough
therapies in the pipeline. Overall market decline will be signifi cant by
2015, but current market leaders are staking out new territories to defend
their franchises.
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At present, because all marketed atypicals (except clozapine) are expensive,
cost is not generally a factor in a physician' s choice of agent. That will
change when the patent for branded risperidone expires. What factors do
physicians consider in prescribing? How will prescribing change when
lower-cost generics are available? How will payers respond to availability of
generic risperidone?
Pending genericization and a less than robust pipeline threaten the historic
growth of the antipsychotics marketplace. What kind of sales are
antipsychotics likely to generate in 2010? In 2015? What is the outlook for
emerging atypicals?
A variety of tactics are available to manufacturers of current and emerging
atypicals. What specifi c strategies are companies pursuing? Will today' s
prominent players continue to lead the marketplace?
Scope
- The current market: Key players, atypical antipsychotics, current
market leaders, indications, sales, major markets.
- Market outlook: Sales trends through 2015, key players,
"new-generation" atypicals,genericization, reimbursement issues, declining
markets.
- Survival strategies: Life-cycle management, line extensions, new
indications and patient populations.
Mentioned in This Report-Companies
- Astellas
- AstraZeneca
- Bristol-Myers Squibb
- Eli Lilly
- Johnson & Johnson
- Lundbeck
- Novartis
- Organon
- Otsuka
- Pfi zer
- Solvay
- Wyeth