Diabetes Monitoring Products & Therapy to 2008

TABLE OF CONTENTS

INTRODUCTION

I. EXECUTIVE SUMMARY

II. MARKET ENVIRONMENT

• General
• Economic Factors
  • Recent Economic Trends
  • Long-Term Economic Projections
• Demographic Patterns
• Trends in Health Care
  • Health Insurance
  • National Health Expenditures
  • Medical Providers
  • Patient Activity
• Diabetes Overview
  • Incidence
    • Type 1 Diabetes
    • Type 2 Diabetes
    • Gestational Diabetes
  • Treatment Costs
  • World Diabetes Conditions

III. TECHNOLOGY OVERVIEW

• General
• Biosensors
• Recombinant DNA
• Stem Cell Research
• Insulin Dosage Formulations
• Other Technologies
  • Chiral Chemistry
  • Combinatorial Chemistry
  • Monoclonal Antibodies
  • Nanotechnology

IV. PRODUCT OVERVIEW

• General
• Market Trends 1993-2003
• International Markets
  • US Trade
  • World Market Outlook

V. BLOOD GLUCOSE MONITORING & DIABETES DIAGNOSTIC PRODUCTS

• General
• Blood Glucose Monitoring Products
  • Blood Glucose Test Strips
    • Technologies
    • Producers
    • Electrochemical Test Strips
    • Photometer Reflectance Test Strips
  • Blood Glucose Monitors
    • Monitor Features & Capabilities
    • Point-In-Time Self-Testing Monitors
    • Professional Blood Glucose Monitoring Systems
    • Continuous Self-Testing Monitors
    • Blood Glucose Monitors in Development
  • Blood Glucose Testing Supplies
    • Lancets
    • Lancing Devices
    • Biosensors
• Diabetes Diagnostic Products
  • Hemoglobin A1c Testing Products
  • Blood Glucose Reagents & Test Kits
  • Microalbumin Testing Products
  • Ketone Testing Products
  • Other Diabetes Diagnostic Products

VI. INSULIN DELIVERY SYSTEMS

• General
• Insulin Injector Systems
  • Pen Injectors
    • Disposable Pen Injectors
    • Reusable Pen Injectors
  • Syringe & Needle Sets
  • Needleless Jet Injectors
  • Other Insulin Injection Supplies
    • Infectious Waste Disposal Supplies
    • Injection Aids
• Insulin Pumps & Accessories
  • External Pumps
    • Pump Advantages
    • Pump Disadvantages
    • Producers & Products
  • Implantable Pumps
  • Pump Accessories
• Insulin Dosage Formulations
  • Types of Insulin
  • Insulin Producers & Products
  • Insulin Vials
  • Insulin Cartridges
  • Inhalation Insulin
  • Oral Insulin
  • Transdermal Insulin
  • Stem Cell Therapies

VII. ORAL ANTI-DIABETIC AGENTS

• General
• Thiazolidinediones (TZDs)
  • Indications & Actions
  • Products & Producers
  • Troglitazone
  • Pioglitazone HCl & Rosiglitazone Maleate
• Biguanides
  • Indications & Actions
  • Products & Producers
• Sulfonylureas
  • Indications & Actions
  • Products & Producers
• Meglitinides
  • Indications & Actions
  • Products & Producers
• Enzyme Inhibitors
  • Indications & Actions
  • Products & Producers
• Peptide Agonists
  • GLP-1 Agonists
  • LAF237
  • MK0431
  • Other Peptide Agonists
• Non-TZD Peroxisome Proliferator-Activated Receptors
• Other Oral Anti-Diabetic Agents

VIII. MARKETS

• General
• Home Health Care Market
• Primary Health Care Market
• Other Markets

IX. INDUSTRY STRUCTURE

• General
• Market Share
• Competitive Strategies
• Mergers & Acquisitions
• Licensing & Related Agreements
• Regulatory Considerations
• Research & Development
• Marketing & Distribution
• Manufacturing
• Company Profiles
  • Abbott Laboratories
  • Alkermes Incorporated
  • Aradigm Corporation
  • Aventis SA, see Sanofi-Aventis
  • Bayer AG
  • Becton, Dickinson and Company
  • Bristol-Myers Squibb Company
  • Cygnus Incorporated
  • Disetronic Group, see Roche Holding Limited
  • Emisphere Technologies Incorporated
  • GlaxoSmithKline plc
  • IVAX Corporation
  • Johnson & Johnson
  • Kos Pharmaceuticals Incorporated
  • LifeScan Incorporated, see Johnson & Johnson
  • Lilly (Eli) and Company
  • MannKind Corporation
  • Medtronic Incorporated
  • Merck & Company Incorporated
  • Novartis International AG
  • Novo Nordisk A/S
  • OSI Pharmaceuticals Incorporated
  • Pfizer Incorporated
  • Prosidion Limited, see OSI Pharmaceuticals
  • Roche Holding Limited
  • Sandoz Generics, see Novartis International AG
  • Sanofi-Aventis
  • Takeda Pharmaceutical Company Limited
  • Terumo Corporation
  • TheraSense Incorporated, see Abbott Laboratories

LIST OF TABLES

SECTION I -- EXECUTIVE SUMMARY

• Summary Table

SECTION II -- MARKET ENVIRONMENT

• 1 Macroeconomic Indicators
• 2 Population & Age Distribution
• 3 National Health Expenditures by Type
• 4 Medical Providers
• 5 Patient Activity
• 6 Diabetes Conditions
• 7 Diabetes Expenditures
• 8 World Diabetes Conditions

SECTION IV -- PRODUCT OVERVIEW

• 1 Diabetes Monitoring Products & Therapies Demand by Product Group
• 2 Diabetes Monitoring Products & Therapies - Demand Patterns, 1993-2003
• 3 US Trade in Diabetes Monitoring Products & Therapies
• 4 World Diabetes Monitoring Products & Therapies Demand

SECTION V -- BLOOD GLUCOSE MONITORING & DIABETES DIAGNOSTIC PRODUCTS

• 1 Blood Glucose Monitoring & Diabetes Diagnostic Products Demand
• 2 Blood Glucose Monitoring Products Demand by Type
• 3 Blood Glucose Test Strips Demand by Type
• 4 Blood Glucose Test Strips - Selected Characteristics
• 5 Electrochemical (EC) Blood Glucose Test Strips Demand
• 6 Photometer Reflectance (PR) Test Strips Demand
• 7 Blood Glucose Monitors Demand by Type
• 8 Blood Glucose Monitors - Selected Characteristics
• 9 Point-In-Time Self-Testing Blood Glucose Monitors Demand
• 10 Professional Use Blood Glucose Monitors Demand
• 11 Continuous Blood Glucose Monitors Demand
• 12 Blood Glucose Testing Supplies Demand by Type
• 13 Lancets Demand
• 14 Lancing Devices Demand
• 15 Biosensors Demand
• 16 Diabetes Diagnostic Products Demand by Type
• 17 Hemoglobin A1c Testing Products Demand
• 18 Blood Glucose Reagents & Test Kits Demand
• 19 Microalbumin Testing Products Demand
• 20 Ketone Testing Products Demand
• 21 Other Diabetes Diagnostic Products Demand

SECTION VI -- INSULIN DELIVERY SYSTEMS

• 1 Insulin Delivery Systems Demand by Type
• 2 Insulin Injector Systems Demand
• 3 Insulin Pen Injector Demand
• 4 Disposable Insulin Pen Injector Demand
• 5 Reusable Insulin Pen Injector Demand
• 6 Insulin Syringe & Needle Set Demand
• 7 Needleless Insulin Jet Injector Demand
• 8 Other Insulin Injector Supply Demand
• 9 Insulin Pump & Accessory Demand
• 10 External Insulin Pump Demand
• 11 Implantable Insulin Pump Demand
• 12 Insulin Pump Accessory Demand
• 13 Insulin Demand by Dosage Formulation
• 14 Insulin Vial Demand
• 15 Insulin Cartridge Demand

SECTION VII -- ORAL ANTI-DIABETIC AGENTS

• 1 Oral Anti-Diabetic Agents Demand
• 2 Thiazolidinediones (TZDs) Demand
• 3 Biguanides Demand
• 4 Sulfonylureas Demand
• 5 Meglitinides Demand
• 6 Enzyme Inhibitors Demand
• 7 Peptide Agonist Demand
• 8 Non-TZD PPARs Demand
• 9 Other Oral Anti-Diabetic Agents Demand

SECTION VIII -- MARKETS

• 1 Diabetes Monitoring Products & Therapies Demand by Market
• 2 Home Health Care Market -- Diabetes Monitoring Products & Therapies
• 3 Primary Health Care Market -- Diabetes Monitoring Products & Therapies
• 4 Other Markets -- Diabetes Monitoring Products & Therapies

SECTION IX -- INDUSTRY STRUCTURE

• 1 Diabetes Monitoring Products & Therapies Sales by Company, 2003
• 2 Selected Acquisitions & Divestitures
• 3 Selected Cooperative Agreements

LIST OF CHARTS

SECTION IV -- PRODUCT OVERVIEW

• 1 Diabetes Monitoring Products & Therapies Demand by Product Group, 2003

SECTION V -- BLOOD GLUCOSE MONITORING & DIABETES DIAGNOSTIC PRODUCTS

• 1 Blood Glucose Monitoring & Diabetes Diagnostic Products Demand by Type, 2003

SECTION VI -- INSULIN DELIVERY SYSTEMS

• 1 Insulin Delivery Systems Demand by Type, 2003

SECTION VII -- ORAL ANTI-DIABETIC AGENTS

• 1 Oral Anti-Diabetic Agents Demand by Type, 2003

SECTION VIII -- MARKETS

• 1 Diabetes Monitoring Products & Therapies Demand by Market, 2003

SECTION IX -- INDUSTRY STRUCTURE

• 1 Diabetes Monitoring Products & Therapies Market Share, 2003