Nanotechnology in Healthcare to 2011

Table of Contents

INTRODUCTION

I. EXECUTIVE SUMMARY

II. MARKET ENVIRONMENT

• General
• Macroeconomic Outlook
• Demographic Trends
• Health Care Trends
  • Medical Conditions
    • Chronic Conditions
    • Acute Conditions
  • Health Insurance & Reimbursement
  • National Health Expenditures
  • Medical Providers
    • Hospitals
    • Outpatient Facilities
    • Physicians
    • Dentists
    • Other Health Care Providers
  • Patient Activity
    • Surgical Procedures
    • Outpatient Visits
    • Diagnostic Tests
• Medical Product Demand
  • Pharmaceuticals
  • Diagnostic Products
    • In Vitro Diagnostic (IVD) Products
    • In Vivo Imaging Agents
  • Medical Supplies & Devices

III. NANOTECHNOLOGY OVERVIEW

• General
• Product Groups
• Regulatory Trends
  • Pharmaceuticals
  • Diagnostic Products
  • Medical Supplies & Devices
  • Current Good Manufacturing Practices (cGMPs)
• Investment Environment
• International Markets

IV. NANOMATERIALS

• General
• Monoclonal Antibodies
• DNA Materials
• Nanoparticles
• Nanotubes & Nanowires
• Dendrimers
• Fullerenes
• Quantum Dots
• Other Nanomaterials

V. NANOMEDICINES

• General
• Product Groups
• Monoclonal Antibodies
  • Marketed Products
  • Products in Development
• Polymer-Based Nanomedicines
  • Marketed Products
  • Developmental Activities
• Other Nanomedicines
  • Nanocrystal Therapies
  • Liposomes
    • Marketed Products
    • Products in Development
  • All Other Nanomedicines
    • Marketed Products
    • Products in Development

VI. NANODIAGNOSTICS

• General
• In Vitro Diagnostics
  • Monoclonal Antibodies
    • Immunological Reagents & Test Kits
    • Immunohematology
    • Cellular Analysis
    • Research Reagents
  • DNA Testing Materials
    • Amplified DNA Probes
    • Direct DNA Probes
    • DNA Microarrays
    • Other DNA Testing Materials
• In Vivo Diagnostics
  • MRI Imaging Agents
    • Advanced Magnetics
    • Kereos
    • Other Development Stage Compounds
  • Other Diagnostic Imaging Agents

VII. NANOTECH MEDICAL SUPPLIES & DEVICES

• General
• Orthopedic Products
  • Bone Cement
  • Bone Substitutes
  • Orthopedic Implants
• Wound Management Products
  • Wound Closures
  • Wound Dressings
• Dental Products
• Surgical Products
• Ophthalmic Products
• Other Nanotechnology Medical Supplies & Devices
  • Disinfectants
  • Cardiac Implants
  • Cochlear Implants
  • Catheters
  • Neuron Regenerators
  • Artificial Skin

VIII. APPLICATIONS

• General
• Cancer
  • Epidemiological Trends
  • Nanomedicines
  • Diagnostics
• Central Nervous System Conditions
  • Epidemiological Trends
  • Nanomedicines
  • Diagnostics
  • Medical Supplies & Devices
• Infective & Parasitic Conditions
  • Epidemiological Trends
  • Nanomedicines
  • Diagnostics
• Cardiovascular Conditions
  • Epidemiological Trends
  • Nanomedicines
  • Diagnostics
  • Medical Supplies & Devices
• Other Applications

IX. INDUSTRY STRUCTURE

• General
• Market Share
• Competitive Strategies
• Licensing Agreements
• Research & Development
• Marketing & Distribution
• Manufacturing

• Company Profiles
  • Abbott Laboratories
  • Abraxis BioScience Incorporated
  • Access Pharmaceuticals Incorporated
  • Advanced Magnetics Incorporated
  • Advion BioSciences Limited
  • Alnis BioSciences Incorporated
  • Altair Nanotechnologies Incorporated
  • ALZA Corporation, see Johnson & Johnson
  • American BioScience, see Abraxis BioScience
  • American Pharmaceutical Partners, see Abraxis BioScience
  • Amgen Incorporated
  • Angstrom Medica Incorporated
  • Arrowhead Research Corporation
  • AstraZeneca plc
  • Avidimer Therapeutics Incorporated
  • Baxter International Incorporated
  • Bayer AG
  • BioDelivery Sciences International
  • BioForce Nanosciences Holdings Incorporated
  • Biogen Idec Incorporated
  • Biophan Technologies Incorporated
  • BioSante Pharmaceuticals Incorporated
  • BioTrove Incorporated
  • Bristol-Myers Squibb Company
  • C Sixty, see Carbon Nanotechnologies
  • Carbon Nanotechnologies Incorporated
  • CritiTech Incorporated
  • Crystalplex Corporation
  • CytImmune Sciences Incorporated
  • Danaher Corporation
  • Dendritic NanoTechnologies, see Starpharma Holdings
  • Dow Chemical Company
  • Elan Corporation plc
  • Enzon Pharmaceuticals Incorporated
  • eSpin Technologies Incorporated
  • Ferro Corporation
  • Flamel Technologies SA
  • GeneFluidics Incorporated
  • Genentech Incorporated
  • Health Plus International Incorporated
  • Improvita Health Products Incorporated
  • Insert Therapeutics, see Arrowhead Research
  • International Business Machines Corporation
  • Intradigm Corporation
  • Introgen Therapeutics Incorporated
  • Invitrogen Corporation
  • Johnson & Johnson
  • Kerr Corporation, see Danaher Corporation
  • Lavipharm Corporation
  • Luna Innovations Incorporated
  • Mallinckrodt, see Tyco International
  • Merck & Company Incorporated
  • Mersana Therapeutics Incorporated
  • NanoBio Corporation
  • NanoBioMagnetics Incorporated
  • NanoBioTec GmbH
  • Nanobiotix SA
  • NanoCarrier Company Limited
  • NanoCure Corporation, see Avidimer Therapeutics
  • NanoDel Technologies GmbH
  • Nanodisc Incorporated
  • Nanogen Incorporated
  • NanoHorizons Incorporated
  • NanoInk Incorporated
  • NanoLab
  • NanoMaterials Technology Pte Limited
  • NanoMed Pharmaceuticals Incorporated
  • Nanomix Incorporated
  • Nanopharma Corporation, see Mersana Therapeutics
  • Nanoplex Technologies, see Oxonica Limited
  • Nanospectra Biosciences Incorporated
  • Nanosys Incorporated
  • Nektar Therapeutics
  • Novagali Pharma SA
  • Novavax Incorporated
  • NUCRYST Pharmaceuticals Corporation
  • Ortho Biotech Products, see Johnson & Johnson
  • Orthovita Incorporated
  • Oxonica Limited
  • Pfizer Incorporated
  • PharmaSol GmbH
  • pSivida Limited
  • Quantum Dot, see Invitrogen Corporation
  • Roche Holding Limited
  • Salvona LLC
  • Sensatex Incorporated
  • Siemens AG
  • SkyePharma plc
  • Smiths Group plc
  • Soliqs, see Abbott Laboratories
  • Spire Corporation
  • Starpharma Holdings Limited
  • Sybron Dental Specialties, see Danaher
  • Tailored Materials Corporation Incorporated
  • Teva Pharmaceutical Industries Limited
  • 3M Company
  • Triton BioSystems Incorporated
  • Tyco International Limited
  • Wyeth

LIST OF TABLES

SECTION I -- EXECUTIVE SUMMARY

• Summary Table

SECTION II -- MARKET ENVIRONMENT

• 1 Macroeconomic Indicators
• 2 Population by Age Group
• 3 Medical Conditions by Duration & Type
• 4 National Health Expenditures by Type
• 5 Selected Medical Providers by Type
• 6 Selected Patient Activity by Type
• 7 Medical Product Demand by Type
• 8 Pharmaceutical Demand by Therapeutic Class
• 9 Diagnostic Product Demand by Type

SECTION III -- NANOTECHNOLOGY OVERVIEW

• 1 Nanotechnology Medical Product Demand by Type
• 2 R&D Investment in Nanotechnology Medical Products

SECTION V -- NANOMEDICINES

• 1 Nanomedicine Demand by Therapeutic Class
• 2 Nanomedicine Demand by Product Group
• 3 Therapeutic Monoclonal Antibody Demand
• 4 Therapeutic Monoclonal Antibodies Approved for US Sale
• 5 Therapeutic Monoclonal Antibodies -- US Sales by Product, 2001 & 2006
• 6 Polymer-Based Nanomedicine Demand
• 7 Polymer-Based Nanomedicines Approved for US Sale
• 8 Polymer-Based Nanomedicines -- US Sales by Product, 2001 & 2006
• 9 Other Nanomedicine Demand
• 10 Nanocrystal Medicines Approved for US Sale
• 11 Liposomal Therapies Approved for US Sale
• 12 Other Nanomedicines Approved for US Sale

SECTION VI -- NANODIAGNOSTICS

• 1 Nanotechnology-Based Diagnostic Product Demand by Segment
• 2 Nanotechnology In Vitro Diagnostic Product Demand by Type
• 3 Monoclonal Antibody-Based Diagnostic Product Demand by Type
• 4 Monoclonal Antibody-Based Immunological Reagent & Test Kit Demand
• 5 Monoclonal Antibody-Based Immunohematology Reagent & Test Kit Demand
• 6 Monoclonal Antibody-Based Cellular Analysis Reagent & Test Kit Demand
• 7 Monoclonal Antibody-Based Research Reagent Demand
• 8 DNA Testing Material Demand by Type
• 9 Amplified DNA Probe Demand
• 10 Direct DNA Probe Demand
• 11 DNA Microarray Demand
• 12 Other DNA Testing Material Demand by Type
• 13 Nanotechnology In Vivo Diagnostic Product Demand

SECTION VII -- NANOTECH MEDICAL SUPPLIES & DEVICES

• 1 Nanotechnology Medical Supply & Device Demand by Product Group
• 2 Nanotechnology Orthopedic Product Demand
• 3 Nanopolymer Bone Cement Demand
• 4 Nanomaterial Bone Substitute Demand
• 5 Nanotechnology Orthopedic Implant Demand by Type
• 6 Nanotechnology Wound Management Product Demand
• 7 Nanotechnology Wound Closure Demand
• 8 Nanotechnology Wound Dressing Demand
• 9 Nanotechnology Dental Product Demand
• 10 Nanotechnology Surgical Product Demand
• 11 Nanotechnology Ophthalmic Product Demand
• 12 Other Nanotechnology Medical Supply & Device Demand

SECTION VIII -- APPLICATIONS

• 1 Nanotechnology Medical Product Demand by Application
• 2 Nanotechnology Cancer Product Demand
• 3 Nanotechnology Central Nervous System Product Demand
• 4 Nanotechnology Product Demand for Infective & Parasitic Conditions
• 5 Nanotechnology Cardiovascular Product Demand
• 6 Nanotechnology Medical Product Demand in Other Applications by Product Class & Type

SECTION IX -- INDUSTRY STRUCTURE

• 1 Selected Cooperative Agreements

LIST OF CHARTS

SECTION III -- NANOTECHNOLOGY OVERVIEW

• 1 Nanotechnology Medical Product Demand by Type, 2011

SECTION V -- NANOMEDICINES

• 1 Nanomedicine Demand by Therapeutic Class, 2011
• 2 Nanomedicine Demand by Product Group, 2011

SECTION VI -- NANODIAGNOSTICS

• 1 Nanodiagnostics Demand by Product Group, 2011

SECTION VII -- NANOTECH MEDICAL SUPPLIES & DEVICES

• 1 Nanotech Medical Supply & Device Demand by Product Group, 2011

SECTION VIII -- APPLICATIONS

• 1 Nanotechnology Medical Product Demand by Application, 2011

SECTION IX -- INDUSTRY STRUCTURE

• 1 Nanotechnology Medical Product Market Share, 2006