Drug Delivery Systems

Table of Contents

INTRODUCTION

I. EXECUTIVE SUMMARY

II. MARKET ENVIRONMENT

• General
• Macroeconomic Trends
• Demographic Patterns
• Health Care Trends
  • Health Insurance
  • Medical Conditions
    • Acute Conditions
    • Chronic Conditions
  • National Health Expenditures
  • Medical Providers
    • Outpatient Clinics
    • Skilled Nursing Homes
    • Acute Care Hospitals
    • Physicians
  • Patient Activity
    • Acute Care Hospital Admissions
    • Surgical Procedures
    • Outpatient Visits
• Pharmaceutical Market Overview
  • Regulation
  • Research & Development
  • Demand Patterns & Forecasts
    • Therapeutic Classes
    • Generic Competition
    • Dosage Formulations
    • Regulatory Classifications

III. DRUG DELIVERY MATERIALS

• General
• Sterile & Purified Water
• Synthetic Polymers
  • Polyethylene Glycol (PEG)
  • Acrylic Polymers
    • Carbomers
    • Methacrylate Copolymers
  • Polyethylene Oxide
  • Polyvinyl Alcohol
  • Other Synthetic Polymers
• Cellulose Derivatives
  • Ethyl Cellulose
  • Hydroxypropyl Methylcellulose (HPMC)
  • Other Cellulose Derivatives
• Minerals
  • Mineral Hydrocarbons
    • Petrolatum
    • Mineral Oil
    • Mineral Hydrocarbon Waxes
  • Other Minerals
    • Attapulgite
    • Calcium Carbonate
    • Calcium Silicate
    • Electrolytes
  • Other Drug Delivery Materials
  • Starch Compounds
    • Cyclodextrins
    • Dextrates
    • Dextrin
    • Maltodextrin
  • Sugars & Polyols
    • Sucrose
    • Sorbitol
    • Lactose
    • Mannitol
  • Natural Gums
  • All Other Drug Delivery Materials

IV. DRUG DELIVERY SYSTEMS OVERVIEW

• General
• Types of Drug Delivery Systems
• Historical Demand Patterns
• Regulation
• Research & Development
• US Trade
• International Markets

V. ORAL DRUG DELIVERY SYSTEMS

• General
• Controlled-Release Formulations
  • Technologies
  • Coated Systems
  • Diffusion Systems
  • Reservoir Systems
• Chewable Tablets
• Orally Disintegrating Tablets
• Nanoparticulate Formulations
  • Ethical Pharmaceuticals
  • Over-the-Counter Drugs
• Transmucosal Formulations

VI. PARENTERAL DRUG DELIVERY SYSTEMS

• General
• Therapeutic Monoclonal Antibodies
  • Technology
  • Anti-Cancer Agents
  • Other Therapeutic Monoclonal Antibodies
  • Products in Development
• Prefilled Syringes
  • Applications
  • Injectors
  • Cartridges & Insulin Pens
• Encapsulated Systems
  • Polymer-Protected Systems
    • PEGylated Formulations
    • Other Polymer-Protected Pharmaceuticals
• Liposomes
• Developmental Activities
• Premixed IV Solutions
  • Mini-Bags
  • Bag/Vial Infusion Systems
  • Applications

VII. INHALATION, TRANSDERMAL & IMPLANTABLE DRUG DELIVERY SYSTEMS

• General
• Inhalation Drug Delivery Systems
  • Dry Powder Formulations
    • Devices & Technologies
    • Applications
  • Metered Dose Formulations
    • Devices & Technologies
    • Applications
• Transdermal Drug Delivery Systems
  • Products & Technologies
  • Developers & Suppliers
  • Applications
• Implantable Drug Delivery Systems
  • Drug-Eluting Stents
  • Drug Inserts
  • Brachytherapy

VIII. APPLICATIONS

• General
• Central Nervous System Agents
• Respiratory Agents
• Hormones & Related Agents
• Gastrointestinal Agents
• Cardiovascular Agents
• Anti-Infective Agents
• Nutritional Agents
• Biologicals
• Genito-Urinary Agents
• Other Therapies

IX. INDUSTRY STRUCTURE

• General
• Developmental Revenues
• Market Share
• Competitive Strategies
• Mergers & Acquisitions
• Licensing & Related Agreements
• Marketing & Distribution
• Manufacturing

COMPANY PROFILES

• Alkermes Incorporated
• AptarGroup Incorporated
• Aradigm Corporation
• Associated British Foods plc
• Aveva Drug Delivery Systems, see Nitto Denko
• Baxter International Incorporated
• Becton, Dickinson and Company
• Bespak, see Consort Medical
• Cardinal Health Pharmaceutical Technologies and Services, see Catalent Pharma Solutions
• Catalent Pharma Solutions Incorporated
• Cephalon Incorporated
• CIMA LABS, see Cephalon
• Consort Medical plc
• Corium International Incorporated
• CyDex Pharmaceuticals Incorporated
• Depomed Incorporated
• Dow Corning Corporation
• DURECT Corporation
• Elan Corporation plc
• Emisphere Technologies Incorporated
• Encore Medical, see ReAble Therapeutics
• Eurand NV
• Flamel Technologies SA
• Genzyme Corporation
• Hospira Incorporated
• IOMED, see ReAble Therapeutics
• Johnson & Johnson
• Nastech Pharmaceutical Company Incorporated
• Nektar Therapeutics
• Nitto Denko Corporation
• NOF Corporation
• Penwest Pharmaceuticals Company
• ReAble Therapeutics Incorporated
• Safety Syringes Incorporated
• SPI Pharma, see Associated British Foods
• StrataGent Life Sciences, see Corium International
• 3M Company
• Valeritas LLC
• Valois SAS, see AptarGroup
• Other Companies Mentioned in Study

LIST OF TABLES

SECTION I -- EXECUTIVE SUMMARY

• Summary Table

SECTION II -- MARKET ENVIRONMENT

• Macroeconomic Indicators
• Population by Age Group
• Acute Conditions by Type
• Chronic Conditions by Type
• National Health Expenditures by Type
• Medical Providers by Type
• Patient Activity by Type
• Pharmaceutical Demand by Therapeutic Class
• Pharmaceutical Demand by Commercial Status
• Pharmaceutical Demand by Dosage Formulation
• Pharmaceutical Demand by Regulatory Classification

SECTION III -- DRUG DELIVERY MATERIALS

• Drug Delivery Material Demand by Type
• Sterile & Purified Water Demand in Drug Delivery
• Synthetic Polymer Demand in Drug Delivery
• Cellulose Derivative Demand in Drug Delivery
• Mineral Demand in Drug Delivery
• Other Material Demand in Drug Delivery

SECTION IV -- DRUG DELIVERY SYSTEMS OVERVIEW

• Drug Delivery System Demand by Dosage Formulation
• Drug Delivery System Demand, 1997-2007
• US Trade in Drug Delivery Systems
• World Drug Delivery System Demand by Region

SECTION V -- ORAL DRUG DELIVERY SYSTEMS

• Oral Drug Delivery System Demand by Type
• Oral Controlled-Release Drug Delivery System Demand
• Coated Controlled-Release Drug Delivery System Demand
• Diffusion Controlled-Release Drug Delivery System Demand
• Reservoir Controlled-Release Drug Delivery System Demand
• Chewable Tablet Demand by Therapeutic Class
• Orally Disintegrating Tablet Demand by Therapeutic Class
• Nanoparticulate Oral Drug Delivery System Demand by Therapeutic Class
• Oral Transmucosal Drug Delivery System Demand by Therapeutic Class

SECTION VI -- PARENTERAL DRUG DELIVERY SYSTEMS

• Parenteral Drug Delivery System Demand by Type
• Therapeutic Monoclonal Antibody Demand by Therapeutic Class
• Therapeutic Monoclonal Antibodies Approved for US Sale
• Prefilled Syringe Demand by Therapeutic Class
• Encapsulated Parenteral Drug Delivery System Demand by Type & Therapeutic Class
• Premixed IV Solution Demand by Therapeutic Class

SECTION VII -- INHALATION, TRANSDERMAL & IMPLANTABLE DRUG DELIVERY SYSTEMS

• Other Drug Delivery System Demand by Type
• Inhalation Drug Delivery System Demand by Type & Therapeutic Class
• Transdermal Drug Delivery System Demand by Therapeutic Class
• Implantable Drug Delivery System Demand by Type & Therapeutic Class

SECTION VIII -- APPLICATIONS

• Drug Delivery System Demand by Therapeutic Class
• Central Nervous System Drug Delivery Demand by Type
• Respiratory Drug Delivery Demand by Type
• Hormone & Related Drug Delivery Demand by Type
• Gastrointestinal Drug Delivery System Demand by Type
• Cardiovascular Drug Delivery System Demand by Type
• Anti-Infective Drug Delivery System Demand by Type
• Nutritional Delivery System Demand by Type
• Biological Delivery System Demand by Type
• Genito-Urinary Drug Delivery System Demand
• Drug Delivery System Demand in Other Therapies

SECTION IX -- INDUSTRY STRUCTURE

• Drug Delivery Revenues by Company, 2007
• Selected Acquisitions & Divestitures
• Selected Cooperative Agreements

LIST OF CHARTS

SECTION III -- DRUG DELIVERY MATERIALS

• Drug Delivery Material Demand by Type, 2007

SECTION IV -- DRUG DELIVERY SYSTEMS OVERVIEW

• Drug Delivery System Demand by Dosage Formulation, 2007

SECTION V -- ORAL DRUG DELIVERY SYSTEMS

• Oral Drug Delivery System Demand by Type, 2007

SECTION VI -- PARENTERAL DRUG DELIVERY SYSTEMS

• Parenteral Drug Delivery System Demand by Type, 2007

SECTION VII -- INHALATION, TRANSDERMAL & IMPLANTABLE DRUG DELIVERY SYSTEMS

• Inhalation, Transdermal & Implantable Drug Delivery System Demand by Type, 2007

SECTION VIII -- APPLICATIONS

• Drug Delivery System Demand by Therapeutic Class, 2007

SECTION IX -- INDUSTRY STRUCTURE

• US Drug Delivery Product Sales by Company, 2007