1 EXECUTIVE SUMMARY
- Introduction
- RNAi Technology in Brief
- Overview of the RNAi Sector
- Scope and Methodology
- Research Scope
- Research Methodology
2 RESEARCH DEVELOPMENTS IN RNAI DESIGN
- Research in the Private Sector
- The Silencer Effect (USA)
- DNA-Based siRNA Constructs (USA)
- Novel RNAi Expression Cassettes (USA)
- Increase RNAi Stability by Chemical Modifications (Belgium)
- Research in the Public Sector
- Inhibit More Genes Simultaneously (USA)
- Take the siDirect Approach (Japan)
- UMMS Provides Exclusive RNAi Technologies (USA)
3 RESEARCH DEVELOPMENTS IN RNAI DELIVERY
- Research in the Private Sector
- Explore Electroporation for Efficient RNAi Delivery (Germany)
- Mouse Musings?Development of RNAi Knockdown in Mice (Germany)
- Novel Lipid and Polymer-Based Transfection Reagents (USA)
- Adenoviral siRNA Library (Belgium)
- Electroporation for Vascular Gene Therapy (USA)
- Research in the Public Sector
- Research Liposome Technology as Delivery Vehicles (Netherlands)
- Nonviral Vectors and Formulations (France)
4 RESEARCH DEVELOPMENTS IN RNAI APPLICATIONS
- Research in the Private Sector
- RNAi Candidate for Liver Cancer (Germany)
- Treat AMD and DR with RNAi (USA)
- C. elegans as an Animal Model for Human Diseases (Belgium)
- RNAi for Nonhuman Therapeutics (USA)
- Novel Nucleotide Chemistry enhances siRNA Therapeutics (Denmark)
- Genome Wide siRNA Screening (Germany)
- siRNA-Based SARS Virus Inhibitors (USA)
- siRNA Agent Slows Macular Degeneration In Animals (USA)
- Research in the Public Sector
- TargeTran siRNA Nanoparticle Technology (USA)
- RNAi Gene Therapy for HIV Infection (USA)
5 RNAI SECTOR--TECHNOLOGY ASSESSMENT
- Sector Trend Analysis
- Technology Trends
- Corporate Collaborations (Part I)
- Corporate Collaborations (Part II)
- RNAi Technology Drivers and Challenges
- Technology Drivers
- Technology Challenges
6 KEY CONTACTS AND NOTEWORTHY PATENTS
- Key Contacts
- Industry Contacts
- University Contacts
- Important Patents
- Patents Part I
- Patents Part II
7 FROST & SULLIVAN 2004 SCIENCE AND TECHNOLOGY AWARDS
- Excellence in Research
- Award Description
- Award Recipient
- Excellence in Technology
- Award Description
- Award Recipient
- Technology Innovation Award
- Award Description
- Award Recipient
8 RELEVANT DECISION SUPPORT DATABASE (DSD) TABLES
- Healthcare Expenditure
- Government Healthcare Expenditure (1999 to 2006)
- Private Healthcare Expenditure (1999 to 2006)
- Total Healthcare Expenditure (1999 to 2006)
- Percentage Healthcare Expenditure (1999 to 2006)
- Per Capita Healthcare Expenditure (1999 to 2006)
- Pharma R & D Expenditure
- Pharma R & D Expenditure (1999 to 2006)
- Percentage Pharma R&D Expenditure (1999 to 2006)
- Cancer Incidence and Mortality
- Breast Cancer Incidence (1999 to 2006)
- Breast Cancer Mortality (1999 to 2006)
- Liver Cancer Incidence (1999 to 2006)
- Liver Cancer Mortality (1999 to 2006)
- Cataract and Diabetes
- Cataract Blindness (1999 to 2006)
- Cataract Surgeries (1999 to 2006)
- Diabetes Incidence (1999 to 2006)
- Diabetes Prevalence (1999 to 2006)
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