Agricultural and Environmental Diagnostics

Table of Contents

I-A. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS

• Study Reliability And Reporting Limitations I-1
• Disclaimers I-2
• Data Interpretation & Reporting Level I-2
• Quantitative Techniques & Analytics I-3
• Product Definitions And Scope of Study I-3
• A. Food Residue Diagnostics I-3
• B. Environmental Testing I-3
• C. Microbiology Testing I-3

I- B. GENERAL OVERVIEW OF THE AGRICULURE INDUSTRY

• Food Security - An Immediate Concern I-4
• Agricultural Biotechnology - Still a Long Way to Go I-4

II-A. EXECUTIVE SUMMARY

1. Industry Overview II-1

• Current & Future Analysis II-1
• Trends & Issues II-1
• Increasing Trend Towards Globalization Spurs Food Diagnostics II-1
• Organic Product Sales Surge due to Decreased Use of Antibiotics II-2
• Food Industry' s Growing Threat: Genetically Modified Organisms (GMOs) II-2
• Food Safety Concerns Fuels Food Safety Testing Market II-2
• Children More Prone to Food Borne Diseases II-3
• Emergence of Rapid Methods II-3
• Ban on Antibiotics Fuel Food Residue Diagnostics II-4
• Opportunities for Genetic and Microbiological in Vitro Diagnostics II-4
• Herbicide Resistant - Pose Problem II-5
• Select Hazardous Herbicides II-5
• Broiler Producers Focused on Producing Coccidiostat-free Birds II-6

2. Agricultural and Environmental Diagnostics-

• An Overview II-7
• Segment Review II-7
• Food Diagnostics II-7
• Environmental Testing II-7
• Microbiology Testing II-7
• Diagnostics In Detail II-8
• Food Testing II-8
• Common Causes of Food Contamination II-8
• Need for Food Testing II-8
• Antibiotic Testing II-8
• Mycotoxin Testing II-8
• Environmental Testing II-9
• Major Environmental Effects of Agricultural Activities II-9
• Agricultural Residues Testing II-9
• Need for Crop Diagnostics II-9
• Crop Diagnostics: Popular Techniques II-10
• Pesticide Residue Testing II-10
• Microbiology Testing II-10
• Increased Focus on Microbial Pathogens II-10
• Top Ten Pathogens Attributed to Food Borne Diseases II-11
• Table 1: Pathogens Attributed to Most Food Borne Diseases (includes corresponding Graph/Chart) II-11
• Microbiological Tests II-11
• Pathogens Testing II-11

3. GMO Testing II-13

• GMO Testing of Seed, Grain, Feed and Food II-13
• Protein Analysis II-14
• DNA Analysis II-14
• PCR Testing Recognized as Most Rigorous, Sensitive, and Accurate Worldwide II-14
• Applications II-14
• Herbicide Tolerance GMO Tests II-15
• Benefits of Herbicide Tolerance GMO tests II-15
• Disadvantages of Herbicide Tolerance GMO Tests II-15

4. Regulatory Environment II-16

• HACCP II-16
• Advantages of HACCP II-16
• HACCP Principles II-17
• Codex Alimentarius Commission Agreement for Pre-Market GMO Testing II-19
• FAO and WHO Propose New Recommendations II-20
• Europe Enforces New Regulatory Framework for Food Contact Materials II-20
• Strict Regime for Approval of GM Organisms II-20
• Food Products Allowed to Contain 1% GMOs II-21
• The 2005 National Residue Monitoring Plan II-21

5. Product Introductions/Innovations II-22

• Four Companies Join Forces Over TRAC © II-22
• IDEXX Launches 1417 Direct-to-Digital Radiography System II-22
• BioMérieux Develops Ready-for-Use Test to Detect Campylobacter II-22
• Strategic Diagnostics Deploy Bacteriophages For Detecting Pathogens II-22
• Biotrace Unveils Cogent MLSII II-22
• Neogen Extends Food Allergen Test Kits With Hazelnut II-23
• Charm Sciences Released novaLUM for ATP Hygiene Monitoring II-23
• Charm Sciences Introduces AllerGiene™ Test for Food Manufacturers II-23
• IDEXX Introduces HerdChek® Swine Influenza Antibody Test Kit II-23
• Neogen Unveils 30-hour, Listeria Enrichment Culture Medium II-23
• Neogen Introduces Tests for Soy Flour II-24
• BioMerieux Launches TEMPO System II-24
• BioControl Presents DNA test for E Coli II-24
• BioMerieux Launches NucliSens easyMAG for Nucleic Acid Extraction II-24
• SDI Introduces New Second-Generation Test II-24
• BioMerieux Rolls Out VITEK 2 Compact II-25
• BioMerieux Introduces NucliSens® miniMAG™ as CE-IVD Approved Platform II-25
• Innovative Biosensors Launches Ultra-Sensitive Test Kit for Pathogenic E. coli O157:H7 II-25
• ARS Develops New Mycotoxin Level Predictor in Corn II-25
• Cooperative Research Centre and Qentec Launch DNATechnology II-26
• Neogen Launches Sanitation Monitoring System II-26
• SDI Introduces Listeria II-26
• BioControl Showcases Lightning MVP for Chemical Concentration II-26
• Neogen Launches Two New Tests II-26
• BioMerieux Releases FoodExpert-ID® II-27
• VICAM Launches New HPLC-Use Immunoaffinity Column II-27
• IDEXX (Europe) Unveils FlockChek APV Antibody Test Kit for Avian Pneumovirus II-27
• Year 2003 in Review II-27
• Year 2002 in Review II-29
• Year 2001 in Review II-30
• Year 2000 in Review II-30

6. Recent Industry Activity II-32

• Waters Corp Acquires Food Safety Technology Assets of VICAM II-32
• Idexx Concludes Merger with Vetlab Services II-32
• IDEXX Acquires VetLINK®, LLC II-32
• Biophage Pharma Collaborates with Héma-Québec II-32
• Neogen Corp Acquires Centrus International II-32
• IDEXX to Expand Facilities II-32
• Warnex Offers PCR-Based Pathogen Detection Test Kits in the US II-33
• Warnex Offer Supply Contract to AmeriSci Bio-Chem II-33
• Biotrace, Pall Corp Sign Global Agreement II-33
• Thailand Supports ASEAN Effort to Standardise GMO II-33
• Biotrace Acquires MicroSafe Group II-33
• Dade Behring, Novation, UHC Collaborate for Microbiology Instruments II-33
• IDEXX Laboratories Inks Agreement to Offer Diagnostic Products II-34
• Response Biomedical, 3M Partner for Microbiology Test II-34
• Innogenetics Achieves Milestone in Development of Rapid Microbiology Testing Assay II-34
• Neogen Corp Acquires UCB' s Dairy Antibiotic Tests Business II-34
• SDI Finalizes Distribution Agreement with US Biosystems II-34
• Biotrace Signs Agreement with Delhaize II-35
• SDI Selected as Custom Antibody Supplier II-35
• Charm Receives USDA GIPSA Approval of ROSA® Aflatoxin P/N II-35
• SDI Signs Distribution Agreement with DuPont II-35
• SDI Confirms Distribution Agreement with MicroBioTests II-35
• Neogen Acquires BAG II-36
• SDI Forges Distribution Agreement with Monitoring Technologies II-36
• IDEXX Acquires Dr. Bommeli AG II-36
• SDI Inks Distribution Agreement with GeneScan II-36
• Biomérieux Accredits Eppendorf for One Step RT-PCR Technology II-36
• SDI Bags UNEP Contract for Testing Systems II-37
• Biotrace Acquires IBP II-37
• BioMérieux and Cepheid Forge Strategic Relationship II-37
• Year 2003 in Review II-37
• Year 2002 in Review II-38
• Year 2001 in Review II-39
• Year 2000 in Review II-41

7. Focus on Select Global Players II-44

• Agdia Inc. (USA) II-44
• Biocontrol Systems Inc.(USA) II-44
• Biomerieux SA (France) II-44
• Biotrace International Plc. (UK) II-45
• Charm Sciences (USA) II-45
• C-Qentec Diagnostics (Australia) II-45
• Idexx Laboratories, Inc. (USA) II-46
• Neogen Corporation (USA) II-46
• R-Biopharm (Germany) II-47
• Strategic Diagnostics Inc. (USA) II-47
• Vicam (USA) II-48

8. Global Market Perspective II-49

• Table 2: World Recent Past, Current & Future Analysis for Agricultural and Environmental Diagnostics by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart) II-49
• Table 3: World 10-Year Perspective for Agricultural and Environmental Diagnostics by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000, 2005 & 2010 (includes corresponding Graph/Chart) II-49
• Table 4: World Recent Past, Current & Future Analysis for Food Residue Diagnostics by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart) II-50
• Table 5: World 10-Year Perspective for Food Residue Diagnostics by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets for Years 2000, 2005 & 2010 (includes corresponding Graph/Chart) II-50
• Table 6: World Recent Past, Current & Future Analysis for Environmental Testing by Geographic Region - US,Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart) II-51
• Table 7: World 10-Year Perspective for Environmental Testing by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets for Years 2000, 2005 & 2010 (includes corresponding Graph/Chart) II-51
• Table 8: World Recent Past, Current & Future Analysis for Microbiology Testing by Geographic Region - US,Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart) II-52
• Table 9: World 10- Year for Microbiology Testing by Geographic Region - US,Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000, 2005& 2010 (includes corresponding Graph/Chart) II-52

II-B. REVIEW OF SELECT TECHNOLOGIES FOR AGRICULTURAL AND ENVIRONMENTAL DIAGNOSTICS

• A. Mycotoxins Testing II-53
• Source of Toxins, and Prevention and Management of Mycotoxicosis II-53
• Research to Control Mycotoxin Contamination of Agricultural Products II-54
• B. Pesticide Residue Testing II-54
• Analytical Techniques for Pesticide Residues in Food II-54
• Sample Preparation II-54
• Extraction II-54
• Cleanup or Isolation II-55
• Determination-chromatograph Separation. II-55
• Gas Chromatography (GC) Separations II-55
• High Performance Liquid Chromatography Separations II-56
• Thin Layer Chromatography (TLC) Separations II-57
• Supercritical Fluid Chromatography (SFC) Separations II-57
• Determination-Detection II-57
• Gas Chromatography Detectors II-57
• High Performance Liquid Chromatography (HPLC)Detectors II-58
• Accurate Detection Possible through Advanced Techniques II-58
• Immunoassay Method II-59
• Advantages II-59
• Drawbacks II-59
• Potential Role of Immunoassay II-59
• C. Microbiology Testing II-60
• Microbiological Tests on Packaged Vegetables, Salads and Fresh-Cut Fruits II-60
• Nucleic Acid Analysis II-61
• Rapid Hygiene Testing II-61

III. MARKET

1. The United States III-1

• A. Market Analysis III-1
• Market Trends and Issues III-1
• Foodborne Ailments - Record High III-1
• Fear of Antibiotic Residues Foster Organic Product Sales III-1
• Animal Health Issues Poses a Threat to Productivity III-1
• Herbicide Resistant Crops - The Other Side III-2
• Consolidation is a Key to Success in Microbiology Tests Market III-2
• Recent Developments III-2
• Array Biosensor Can Detect DON Mycotoxin in Indoor Air and Foods III-2
• CDC Develops RT-PCR Tests for Bird Flu III-3
• FSIS Employs BAX® to Detection E. coli in Raw Meat III-3
• Regulatory Environment III-3
• Role of Federal Safety System in Ensuring Food Safety III-3
• Hazard Analysis and Critical Control Point (HACCP) III-4
• USDA' s Agricultural Marketing Service (AMS) III-4
• Quality Promotion III-4
• Pesticide Data Program III-5
• Pesticide Residues in Food Monitoring Programs by Federal Agencies III-5
• Environmental Protection Agency (EPA) III-5
• Food and Drug Administration (FDA) III-6
• General Commodity Monitoring III-7
• Key Player Review III-7
• Agdia Inc. III-7
• Biocontrol Systems Inc. III-8
• Charm Sciences III-8
• IDEXX Laboratories, Inc. III-8
• Neogen Corporation III-9
• Strategic Diagnostics, Inc. III-9
• VICAM III-10
• Product Introduction/Innovations III-10
• Strategic Developments III-17
• B. Market Analytics III-24
• Table 10: US Recent Past, Current & Future Analysis for Agricultural and Environmental Diagnostics by Product Segments - Food Residue Diagnostics, Environmental Testing and Microbiology Testing Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart) III-24
• Table 11: US 10-Year Perspective for Agricultural and Environmental Diagnostics by Product Segments - Percentage Breakdown of Dollar Sales for Food Residue Diagnostics, Environmental Testing and Microbiology Testing Markets for 2005, 2005 & 2010 (includes corresponding Graph/Chart) III-25

2. Canada III-26

• A. Market Analysis III-26
• Food Safety Testing in Canada III-26
• Pesticide Residue Monitoring in Canada III-26
• Monitoring Programs III-27
• Sampling Strategy for National Surveillance III-27
• Government Support for BSE Detection Program III-27
• Food Testing Agencies III-27
• CFIA: The Canadian Food Inspection Agency III-28
• Health Canada III-29
• Strategic Developments II-29
• B. Market Analytics III-30
• Table 12: Canadian Recent Past, Current & Future Analysis for Agricultural and Environmental Diagnostics by Product Segments - Food Residue Diagnostics, Environmental Testing and Microbiology Testing Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart) III-30
• Table 13: Canadian 10-Year Perspective for Agricultural and Environmental Diagnostics by Product Segments - Percentage Breakdown of Dollar Sales for Food Residue Diagnostics, Environmental Testing and Microbiology Testing Markets for 2005, 2005 & 2010 (includes corresponding Graph/Chart) III-31

3. Japan III-32

• A. Market Analysis III-32
• Mandatory Testing for Genetically Manipulated Food Products III-32
• Strategic Developments III-32
• B. Market Analytics III-33
• Table 14: Japanese Recent Past, Current & Future Analysis for Agricultural and Environmental Diagnostics by Product Segments - Food Residue Diagnostics, Environmental Testing and Microbiology Testing Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart) III-33
• Table 15: Japanese 10-Year Perspective for Agricultural and Environmental Diagnostics by Product Segments - Percentage Breakdown of Dollar Sales for Food Residue Diagnostics, Environmental Testing and Microbiology Testing Markets for 2005, 2005 & 2010 (includes corresponding Graph/Chart) III-33

4. Europe III-34

• A. Market Analysis III-34
• Agricultural Industry Overview III-34
• Concerns Regarding Food Safety Adversely Affects Poultry Sales III-34
• Broiler Producers Preparing for Change III-35
• Safety Concerns III-35
• Microbiology Testing in Europe III-35
• Combating Food Borne Diseases - "European Way" III-35
• Food Poisoning: Steps for Prevention III-35
• Stamping Out Animal Diseases III-36
• Food Safety Regulations in Europe III-36
• Formation of the ENGL II-36
• New Regulatory Framework for Food Contact Materials III-37
• Strict Regime for Approval of GM Organisms III-37
• Food Products Allowed to Contain 1% GMOs III-37
• Food Safety Legislation of the EU III-38
• Food Law: European Parliament Keen to Limit Irradiation List III-38
• EU Grip on GMO Tightens II-38
• EU Establishes New Ceiling for Mycotoxin II-39
• EU Strengthens Safety Rules Governing Food and Feed Additives III-39
• EC Calls on the Food Industry to Adopt Rapid Hygiene Testing III-39
• Product Development III-40
• Strategic Developments III-41
• B. Market Analytics III-42
• Table 16: European Recent Past, Current & Future Analysis for Agricultural and Environmental Diagnostics Market by Geographic Region - France, Germany, Italy, UK, Spain, Russia & Rest of Europe Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart) III-42
• Table 17: European 10-Year Perspective for Agricultural and Environmental Diagnostics Market by Geographic Region - Percentage Breakdown of Dollar Sales for France, Germany, Italy, UK, Spain, Russia & Rest of Europe Markets for Years 2000, 2005 & 2010 (includes corresponding Graph/Chart) III-42
• Table 18: European Recent Past, Current & Future Analysis for Agricultural and Environmental Diagnostics by Product Segments - Food Residue Diagnostics, Environmental Testing and Microbiology Testing Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart) III-43
• Table 19: European 10-Year Perspective for Agricultural and Environmental Diagnostics by Product Segments - Percentage Breakdown of Dollar Sales for Food Residue Diagnostics, Environmental Testing and Microbiology Testing Markets for 2005, 2005 & 2010 (includes corresponding Graph/Chart) III-43

4a. France III-44

• A. Market Analysis III-44
• Product Introductions/Innovations III-44
• Biomerieux SA - Key Player III-46
• B. Market Analytics III-46
• Table 20: French Recent Past, Current & Future Analysis for Agricultural and Environmental Diagnostics by Product Segments - Food Residue Diagnostics, Environmental Testing and Microbiology Testing Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart) III-46
• Table 21: French 10-Year Perspective for Agricultural and Environmental Diagnostics by Product Segments - Percentage Breakdown of Dollar Sales for Food Residue Diagnostics, Environmental Testing and Microbiology Testing Markets for 2005, 2005 & 2010 (includes corresponding Graph/Chart) III-47

4b. Germany III-48

• A. Market Analysis III-48
• Stringent Food Safety Regulations III-48
• Key Player Review III-48
• R-Biopharm III-48
• GeneScan Europe AG III-48
• Strategic Developments III-49
• B. Market Analytics III-49
• Table 22: German Recent Past, Current & Future Analysis for Agricultural and Environmental Diagnostics by Product Segments - Food Residue Diagnostics, Environmental Testing and Microbiology Testing Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart) III-49
• Table 23: German 10-Year Perspective for Agricultural and Environmental Diagnostics by Product Segments - Percentage Breakdown of Dollar Sales for Food Residue Diagnostics, Environmental Testing and Microbiology Testing Markets for 2005, 2005 & 2010 (includes corresponding Graph/Chart) III-50

4c. Italy III-51

• A. Market Analysis III-51
• Food Safety Agreement Signed in Italy III-51
• B. Market Analytics III-51
• Table 24: Italian Recent Past, Current & Future Analysis for Agricultural and Environmental Diagnostics by Product Segments - Food Residue Diagnostics, Environmental Testing and Microbiology Testing Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart) III-51
• Table 25: Italian 10-Year Perspective for Agricultural and Environmental Diagnostics by Product Segments - Percentage Breakdown of Dollar Sales for Food Residue Diagnostics, Environmental Testing and Microbiology Testing Markets for 2005, 2005 & 2010 (includes corresponding Graph/Chart) III-52

4d. The United Kingdom III-53

• A. Market Analysis III-53
• New Scottish Agricultural Policy III-53
• Ireland - Dairy Industry Review III-54
• Biotrace International Plc. - Key Player III-55
• Product Introduction/Innovation II-55
• Strategic Developments III-55
• B. Market Analytics III-58
• Table 26: UK Recent Past, Current & Future Analysis for Agricultural and Environmental Diagnostics by Product Segments - Food Residue Diagnostics, Environmental Testing and Microbiology Testing Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart) III-58
• Table 27: UK 10-Year Perspective for Agricultural and Environmental Diagnostics by Product Segments - Percentage Breakdown of Dollar Sales for Food Residue Diagnostics, Environmental Testing and Microbiology Testing Markets for 2005, 2005 & 2010 (includes corresponding Graph/Chart) III-58

4e. Spain III-59

• Market Analysis III-59
• Table 28: Spanish Recent Past, Current & Future Analysis for Agricultural and Environmental Diagnostics by Product Segments - Food Residue Diagnostics, Environmental Testing and Microbiology Testing Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart) III-59
• Table 29: Spanish 10-Year Perspective for Agricultural and Environmental Diagnostics by Product Segments - Percentage Breakdown of Dollar Sales for Food Residue Diagnostics, Environmental Testing and Microbiology Testing Markets for 2005, 2005 & 2010 (includes corresponding Graph/Chart) III-60

4f. Russia III-61

• A. Market Analysis III-61
• Russia to Revoke Ban on GM Foods III-61
• Labeling Regulations in Russia III-61
• B. Market Analytics III-62
• Table 30: Russian Recent Past, Current & Future Analysis for Agricultural and Environmental Diagnostics by Product Segments - Food Residue Diagnostics, Environmental Testing and Microbiology Testing Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart) III-62
• Table 31: Russian 10-Year Perspective for Agricultural and Environmental Diagnostics by Product Segments - Percentage Breakdown of Dollar Sales for Food Residue Diagnostics, Environmental Testing and Microbiology Testing Markets for 2005, 2005 & 2010 (includes corresponding Graph/Chart) III-62

4g. Rest of Europe III-63

• A. Market Analysis III-63
• Swedish Microbiology Testing Market III-63
• Denmark III-63
• Strategic Developments III-63
• B. Market Analytics III-64
• Table 32: Rest of Europe Recent Past, Current & Future Analysis for Agricultural and Environmental Diagnostics by Product Segments - Food Residue Diagnostics, Environmental Testing and Microbiology Testing Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart) III-64
• Table 33: Rest of Europe 10-Year Perspective for Agricultural and Environmental Diagnostics by Product Segments - Percentage Breakdown of Dollar Sales for Food Residue Diagnostics, Environmental Testing and Microbiology Testing Markets for 2005, 2005 & 2010 (includes corresponding Graph/Chart) III-65

5. Asia-Pacific III-66

• A. Market Analysis III-66
• Australia III-66
• C-Qentec Diagnostics - Key Player III-66
• Korea III-67
• Top Five Processed Products Necessitate Labeling III-67
• China III-67
• Food Safety Monitoring System III-67
• Regulatory Restrictions for Imports and Exports of GM Products III-67
• India III-68
• Upgrading Food Safety Standards III-68
• Brief Review of GM Regulations in Select Countries III-68
• Hong Kong III-68
• Malaysia III-68
• Philippines III-68
• Thailand III-68
• Taiwan III-69
• Strategic Developments III-69
• B. Market Analytics III-71
• Table 34: Asia-Pacific Recent Past, Current & Future Analysis for Agricultural and Environmental Diagnostics by Product Segments - Food Residue Diagnostics, Environmental Testing and Microbiology Testing Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart) III-71
• Table 35: Asia-Pacific 10-Year Perspective for Agricultural and Environmental Diagnostics by Product Segments - Percentage Breakdown of Dollar Sales for Food Residue Diagnostics, Environmental Testing and Microbiology Testing Markets for 2005, 2005 & 2010 (includes corresponding Graph/Chart) III-72

6. Latin America III-73

• A. Market Analysis III-73
• US and Mexico Enter into Agreement to Exchange Food Safety Information III-73
• Pesticide Monitoring in Mexico III-73
• GM Labeling Regulations in Brazilian Market III-75
• Regulatory Framework for Genetically Modified Organisms in Argentina III-75
• Product Introductions/Innovations III-75
• B. Market Analytics III-76
• Table 36: Latin American Recent Past, Current & Future Analysis for Agricultural and Environmental Diagnostics by Product Segments - Food Residue Diagnostics, Environmental Testing and Microbiology Testing Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart) III-76
• Table 37: Latin American 10-Year Perspective for Agricultural and Environmental Diagnostics by Product Segments - Percentage Breakdown of Dollar Sales for Food Residue Diagnostics, Environmental Testing and Microbiology Testing Markets for 2005, 2005 & 2010 (includes corresponding Graph/Chart) III-76

7. Rest of World III-77

• A. Market Analysis III-77
• Labeling Regulatory Framework III-77
• Saudi Arabia III-77
• Strategic Developments III-77
• B. Market Analytics III-78
• Table 38: Rest of World Recent Past, Current & Future Analysis for Agricultural and Environmental Diagnostics by Product Segments - Food Residue Diagnostics,Environmental Testing and Microbiology Testing Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart) III-78
• Table 39: Rest of World 10-Year Perspective for Agricultural and Environmental Diagnostics by Product Segments - Percentage Breakdown of Dollar Sales for Food Residue Diagnostics, Environmental Testing and Microbiology Testing Markets for 2005, 2005 & 2010 (includes corresponding Graph/Chart) III-78

IV. COMPETITION

• 1. A&L Analytical Laboratories, Inc. (USA) IV-1
• 2. Abbey Lane Laboratory LLC (USA) IV-4
• 3. Agdia, Inc. (USA) IV-5
• 4. Agrisense-BCS Limited (UK) IV-8
• 5. Amerisci Bio-Chem (USA) IV-9
• 6. Biocontrol Systems, Inc. (USA) IV-10
• 7. Biogenetic Services, Inc. (USA) IV-11
• 8. Biolog, Inc. (USA) IV-12
• 9. Biomerieux SA (France) IV-14
• Table 40: Nine Months Sales Analysis: 2004-2005 (Nine Months Ended, September) (In € million) IV-15
• Table 41: Nine Months Sales Analysis by Quarter: 2004-2005 (Nine Months Ended, September) (In € million) IV-15
• Table 42: Nine Months Sales Analysis by Geographic Region: 2004-2005 (Nine Months Ended, September) (In € million) IV-15
• 10. Biophage Pharma, Inc. (Canada) IV-19
• 11. Bioreba AG (Switzerland) IV-21
• 12. Bioscience, Inc. (USA) IV-23
• 13. Biotest Diagnostics Corporation (USA) IV-26
• 14. Biotrace International PLC (UK) IV-30
• Table 43: Half Yearly Sales Analysis: 2005-2006 (H1) (In £ million) IV-31
• Table 44: Annual Sales Analysis: 2004-2005 (In £ million) IV-31
• Tecra International Pty Ltd. (Australia) IV-35
• 15. Cellabs Pty., Ltd. (Australia) IV-40
• 16. Center For Environmental Biotechnology, The (USA) IV-41
• 17. Centre For Plant Health (Canada) IV-42
• 18. Cepheid, Inc. (USA) IV-43
• Table 45: First Quarter Sales Analysis: 2005-2006 (In US$ thousands) IV-43
• Table 46: First Quarter Sales Analysis by Segment: 2005-2006 (In US$ thousands) IV-44
• Table 47: Annual Sales Analysis: 2004-2005 (In US$ thousands) IV-44
• Table 48: Annual Sales Analysis by Segment: 2004-2005 (In US$ thousands) IV-44
• 19. Charm Sciences, Inc. (USA) IV-47
• 20. Copesan Services, Inc. (USA) IV-49
• 21. Cortex Biochem, Inc. (USA) IV-50
• 22. C-Qentec Diagnostics Pty., Ltd. (Australia) IV-54
• 23. Cranfield Biotechnology Center (UK) IV-56
• 24. Dade Behring, Inc. (USA) IV-59
• Table 49: Half Yearly Sales Analysis: 2005-2006 (H1) (In US$ million) IV-60
• Table 50: Half Yearly Sales Analysis by Quarter: 2005-2006 (H1) (In US$ million) IV-61
• Table 51: Half Yearly Sales Analysis by Segment: 2005-2006 (H1) (In US$ million) IV-61
• Table 52: Half Yearly Sales Analysis by Geographic Region: 2005-2006 (H1) (In US$ million) IV-61
• Table 53: Annual Sales Analysis: 2004-2005 (In US$ million) IV-61
• Table 54: Annual Sales Analysis by Quarter: 2004-2005 (In US$ million) IV-62
• Table 55: Annual Sales Analysis by Segment: 2004-2005 (In US$ million) IV-62
• Table 56: Annual Sales Analysis by Geographic Region: 2004-2005 (In US$ million) IV-62
• 25. Development Center For Biotechnology (Taiwan) IV-81
• 26. Diagnostix Limited (Canada) IV-84
• 27. Eurofins Genescan, Inc. (USA) IV-87
• 28. Gamma SA (Belgium) IV-87
• 29. Genolife (France) IV-88
• 30. Hema-Quebec (Canada) IV-89
• Table 57: Annual Sales Analysis: 2004-2006 (In US$ million) IV-90
• 31. Hybrizyme Corporation (USA) IV-90
• 32. Idexx Laboratories, Inc. (USA) IV-91
• Table 58: First Quarter Sales Analysis by Segment: 2005-2006 (In US$ million) IV-93
• Table 59: Annual Sales Analysis by Segment: 2004-2005 (In US$ million) IV-93
• Idexx Laboratories Ltd. (UK) IV-97
• 33. Illinois Crop Improvement Association, Inc. (USA) IV-98
• 34. Immuno-Diagnostic Reagents (USA) IV-98
• 35. Immunolab GmbH (Germany) IV-99
• 36. Ingenasa (Spain) IV-99
• 37. Innogenetics NV (Belgium) IV-100
• Table 60: Annual Sales Analysis: 2004-2005 (In € million) IV-101
• Table 61: Annual Sales Analysis by Segment: 2004-2005 (In € million) IV-102
• 38. Innovative Biosensors, Inc. (USA) IV-110
• 39. Innovative Biotechnologies International, Inc. (USA) IV-111
• 40. International Diagnostics Group (UK) Ltd. (UK) IV-112
• 41. Invitrogen Corporation (USA) IV-115
• Table 62: Half Yearly Sales Analysis: 2005-2006 (H1) (In US$ million) IV-116
• Table 63: Half Yearly Sales Analysis by Quarter: 2005-2006 (H1) (In US$ million) IV-116
• Table 64: Annual Sales Analysis: 2004-2005 (In US$ million) IV-116
• Table 65: Annual Sales Analysis by Quarter: 2004-2005 (In US$ million) IV-117
• Table 66: Annual Sales Analysis by Segment: 2004-2005 (In US$ million) IV-117
• 42. Koppert BV (The Netherlands) IV-123
• 43. LGC Limited (UK) IV-124
• 44. Medtox Diagnostics, Inc. (USA) IV-129
• 45. Millipore Corporation (USA) IV-130
• Table 67: Annual Sales Analysis: 2004-2005 (In US$ million) IV-130
• Table 68: Annual Sales Analysis by Segment: 2004-2005 (In US$ million) IV-131
• Table 69: Annual Sales Analysis by Geographic Region: 2004-2005 (In US$ million) IV-131
• 46. Myinefield Research Services Ltd. (UK) IV-136
• 47. National Institute Of Agricultural Botany (UK) IV-137
• 48. NCIMB Ltd. (UK) IV-138
• 49. Neogen Corporation (USA) IV-139
• Table 70: Nine Months Sales Analysis: 2005-2006 (Nine Months Ended, February) (In US$ million) IV-140
• Table 71: Nine Months Sales Analysis by Quarter: 2005-2006 (Nine Months Ended, February) (In US$ million) IV-140
• Table 72: Nine Months Sales Analysis by Segment: 2005-2006 (Nine Months Ended, February) (In US$ million) IV-140
• Table 73: Annual Sales Analysis: 2004-2005 (In US$ million) IV-141
• Table 74: Annual Sales Analysis by Quarter: 2004-2005 (In US$ million) IV-141
• Table 75: Annual Sales Analysis by Segment: 2004-2005 (In US$ million) IV-141
• Table 76: Annual Sales Analysis by Product: 2004-2005 (In US$ million) IV-141
• Neogen Europe Ltd. (UK) IV-149
• 50. Nitrate Elimination Co., Inc. (USA) IV-150
• 51. Novation (USA) IV-151
• 52. PBR Laboratories, Inc. (Canada) IV-153
• 53. PGG Wrightson Limited (New Zealand) IV-155
• Table 77: Annual Sales Analysis: 2005-2006 (In NZ$ million) IV-157
• 54. Princeton Biomeditech Corporation (USA) IV-159
• 55. R-Biopharm AG (Germany) IV-160
• R-Biopharm, Inc. (USA) IV-161
• 56. Response Biomedical Corporation (Canada) IV-162
• Table 78: Annual Sales Analysis: 2004-2005 (In Can$ million) IV-162
• Table 79: Annual Sales Analysis by Quarter: 2004-2005 (In Can$ million) IV-163
• 57. Roche Diagnostics(Schweiz) AG (Switzerland) IV-165
• Table 80: Annual Sales Analysis: 2005-2006 (In CHF million) IV-165
• 58. Rothamsted Research (UK) IV-168
• 59. RQA, Inc. (USA) IV-170
• 60. Scimed Laboratories, Inc. (Canada) IV-171
• 61. Scottish Agricultural Science Agency (SASA) (UK) IV-171
• 62. Strategic Diagnostics, Inc. (USA) IV-172
• Table 81: Half Yearly Sales Analysis: 2005-2006 (H1) (In US$ million) IV-173
• Table 82: Annual Sales Analysis: 2004-2005 (In US$ million) IV-173
• Table 83: Annual Sales Analysis by Product: 2004-2005 (In US$ million) IV-173
• Table 84: Annual Sales Analysis by Geographic Region: 2004-2005 (In US$ million) IV-173
• 63. Third Wave Technologies, Inc. (USA) IV-178
• Table 85: Half Yearly Sales Analysis: 2005-2006 (H1) (In US$ million) IV-178
• Table 86: Annual Sales Analysis: 2004-2005 (In US$ million) IV-178
• 64. United Chemical Technologies, Inc. (USA) IV-180
• 65. Universal Pig Genes, Inc. (USA) IV-181
• 66. Warnex, Inc. (USA) IV-182
• Table 87: Half Yearly Sales Analysis: 2005-2006 (H1) (In US$ million) IV-183
• 67. Waters Corporation (USA) IV-187
• Table 88: Annual Sales Analysis: 2003-2005 (In US$ million) IV-188
• Table 89: Annual Sales Analysis by Quarter: 2004-2005 (In US$ million) IV-188
• Table 90: Annual Sales Analysis by Geographic Region: 2004-2005 (In US$ million) IV-188
• 68. Woods End® Laboratories, Inc. (USA) IV-197