Gene amplification technology has been a backbone technology for the Human Genome Project and is vital in other fields, such as diagnostics. There are more than 50 biotech and diagnostic companies with DNA amplification technology and approximately 30 different gene- and signal-amplification technologies, from polymerase chain reaction to ligase chain reaction, transcription mediated amplification, and dendritic polymers. And these many technologies are being used for an ever-increasing variety of applications in research and clinical settings.
The market for amplification technology is currently in the hundreds of millions of dollars, but as the need for information about genes in genomics and other research progresses, and as clinical diagnostic tools develop, the market for amplification technology will continue to grow. Although PCR is currently the dominant amplification technology, other technologies are emerging to challenge PCR in many areas. Patents, costs, and ease of use of a technique are forces that drive the development of amplification technology and will shape this dynamic market.
This study reviews the landscape in this emerging sector, discussing technologies, applications, competitors, and regulation. In addition, Kalorama has conducted the first ever end-user survey, to determine the preferences of actual researchers using various amplification technologies in various settings and for various applications.
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