Trends in Cell Therapeutics: Promise and Reality

Table of Contents

CHAPTER ONE: Executive Summary

• Scope and Methodology
• Size and Growth of the Market
• Market Trends

CHAPTER TWO: Introduction

• Cell Therapy?Past, Present, and Future
• A Word About Stem Cells
• Disease Opportunities and Scientific Reticence
• Point of View

CHAPTER THREE: Cell Technology Commercialization: The Journey from Bench to Clinic

• Problems with Embryonic Stem Cells: It's More than Ethics
• Adult Stem Cells to the Rescue?
• Autologous, Allogeneic, and Xenogenic Products
• Cell Therapy Equipment and Accessories
• Cloning and Bioengineering Cells and Tissues
• The Journey Continues

CHAPTER FOUR: Market Trends and Issues Population Demographics and The Demand for Cell and Tissue Products

• Patent Issues
• Technology and Reimbursement Issues
• New Technology Commercialization
• Regulatory Affairs
  • The European Union
  • Germany
  • France
  • Spain
  • United Kingdom
  • Sweden
  • Japan
  • China
  • Singapore
  • Israel
  • Canada
  • Australia
  • United States

CHAPTER FIVE: Cell Therapy Applications: Commercial and Non-Commercial Research

• Cancer Vaccines
• Cardiovascular Diseases
• Diabetes
• Electronic Tissue
• Gene / Drug Delivery
• Immune System Modulation
• Nervous System Injuries / Neurological Diseases
• Organ Replacement / Tissue Engineering
• Miscellaneous Applications

CHAPTER SIX: Market Analysis

• Introduction
• Bioengineered Skin Products
• Bone and Cartilage
• Stem Cell Therapy, 2002-2007
• Cell therapy, 2005-2015
• Company Mergers and Closures
• Cell Cloning

CHAPTER SEVEN: Conclusions and Strategic Implications

• First Conclusion
• Implication
• Second Conclusion
• Implication
• Third Conclusion
• Implication
• Fourth Conclusion
• Implication
• Fifth Conclusion
• Implication

CHAPTER EIGHT: Companies and Technologies To Watch

CHAPTER NINE: Company Profiles

• Aastrom Biosciences, Inc.
• Advanced Cell Technology (ACT)
• AmCyte Inc.
• Anthrogenesis (Acquired by Celgene Corp.)
• Artecel Inc. (formerly Artecel Sciences, Inc.)
• Athersys Inc.
• Baxter Healthcare Corporation
• Bioheart Inc.
• BresaGen Ltd.
• Celgene Corporation
• Cell Transplants International, LLC (CTI)
• Celmed BioSciences Inc.
• Chromos Molecular Systems Inc.
• Diatranz, Ltd.
• ES Cell International Pte Ltd (ESI)
• Gamida-Cell Ltd.
• GenVec Inc. / Diacrin
• Geron Corporation
• Immuno-Designed Molecules S.A. (IDM)
• Kourion Therapeutics
• LifeCell Corporation
• Merix Bioscience, Inc.
• MicroIslet Inc.
• Nucleotech LLC
• Osiris Therapeutics Inc.
• Proneuron Biotechnologies Inc.
• Transition Therapeutics Inc.
• ViaCell, Inc.
• Xcyte Therapies, Inc

APPENDIX A: List of Cell Therapy Companies and Their Products

APPENDIX B: Lexicon of Cell Therapy Terms

List of Exhibits

CHAPTER THREE: Cell Technology Commercialization: The Journey from Bench to Clinic

• Table 3-1: Providers of Currently Approved Cell Lines
• Table 3-2: Selected Companies Working on Adult and Stem Cell Therapies
• Table 3-3: Selected Cell Encapsulated Cell Therapeutics
• Table 3-4: Selected Cell Therapy Products using Xenogenic Cells
• Table 3-5: Selected Cell Therapy Equipment and Accessories
• Table 3-6: Selected Cell and Tissue Bioengineered Products

CHAPTER FIVE: Cell Therapy Applications: Commercial and Non-Commercial Research

• Table 5-1: Selected Cancer Vaccine Programs
• Table 5-2: Selected Stem Cell Therapies for Cardiovascular Disease
• Table 5-3: Selected Diabetes Cell Therapy Products
• Table 5-4: Selected Neural Stem Cell Therapies
• Table 5-5: Selected Organ Bioengineering Programs

CHAPTER SIX: Market Analysis

• Table 6-1: Number of Patients in Selected Cell Therapy Target Populations in the United States
• Table 6-2: Worldwide Market for Selected Cell Therapies by Type 2002-2007
• Table 6-3: Sales of the Leading Skin Replacement Products 2002
• Table 6-4: Cell Replacement Procedures by Region 2002-2007
• Figure 6-1: Technology Penetration Forecast for Cell Therapy Technologies

CHAPTER EIGHT: Companies and Technologies to Watch

• Table 8-1: Strength Analysis of 22 Selected Cell Therapy Companies
• Table 8-2: Kalorama's Short List of Cell Therapy Companies