Pharmaceutical Excipients for Oral Formulations, 2nd. Edition

Table of Contents

I. INTRODUCTION

• Study Rationale
• Study Goals
• Scope and Structure
• Methodology
• Target Audience

II. PHARMACEUTICAL EXCIPIENTS: EXECUTIVE SUMMARY

• Global Excipient Market: Background
• Market Size and growth
• Future market trends
• Leading Players
• Industry Structure, Margins and business models
• Future prospects

III. PHARMACEUTICAL EXCIPIENTS: INDUSTRY OVERVIEW

• Industry Overview
• The Pharmaceutical Industry
• The Chemical/Excipient Industry
• Industry Trends
• Issues
• Challenges
• Constraints
• Trends (especially outsourcing and offshore manufacturing)
• Business Opportunities
• Excipient Regulations
• CGMP Practices
• FDA/CDER (Center for Drug Evaluation and Research) Regulations, USP (U.S. Pharmacopoeia) and IPEC v
• (International Pharmaceutical Excipients Council) Monographs
• Excipient Safety Regulations
• Participating Companies
• Research and Development
• Marketing and Distribution
• Pricing and Reimbursement
• Corporate Strategies/SWOT Analysis

IV. PHARMACEUTICAL EXCIPIENTS: TECHNICAL PERSPECTIVES

• Definition and Applications
• Oral delivery (Tablets, etc)
• Topical delivery (ointments and creams)
• Vaginal and Rectal delivery (suppositories)
• Excipient Formulations
• Tablets and Powders
• Capsules and Gels
• Liquid and Aqueous
• Excipient Drug Dissolution Types and Properties
• Immediate (fast-melt/quick dissolving)
• Time-released (sustained/extended release)
• Excipient Manufacturing Methods/Technologies
• Direct-compression/spray drying
• Freeze-drying
• Direct Granulation (wet/dry)
• Molding
• Sublimation
• Cotton-candy Process
• Major End-Uses
• Tablets/Caplets
• Aspirin
• Acetaminophen
• Ibuprofen
• Anti-acids
• Analgesics
• Vitamins
• Other
• Capsules
• Vitamins
• Anti-oxidants
• Other
• Liquid/Aqueous Preparations
• Cough Medications
• Anti-Acids
• Other

V. ORAL EXCIPIENTS: MARKETS AND PRODUCTS

• Global Excipient Market size, share, growth by segment (2007-2012)
• Fillers
• Emollients
• Vehicles
• Coatings
• Disintegrants
• Flavorants
• Osmotic agents
• Colorants
• Anti-caking Agents
• Magnesium Carbonate
• Mannitol
• Sorbitol
• Silica
• Talc
• Erythritol
• Isomalt
• Maltitol
• Tagatose
• Trehalose
• Xylitol
• Binders and Fillers
• Microcrystalline Cellulose (MCC)
• Hydrolyzed Gelatin
• Alginic Acid
• Dextrin
• Glucose (liquid)
• Lactose
• Sucrose
• Dibasic Calcium Phosphate (DCP)
• Coatings
• Enteric Coatings
• Polymer Coatings (acrylics, etc)
• Cellulosics
• Carbohydrates
• Microcrystalline cellulose
• Other
• Disintegrants
• Starches
• Corn Starch
• Dried Starch
• Modified Starch
• Gelatin
• Pregelatinized Starch
• Modified Cellulose
• Gums
• Guar Gum
• Xanthan Gum
• Polymers
• Acrylic Polymers
• Matrix (controlled-release) Polymers
• Alginates
• Other
• Enzymes
• Pepsin
• Trypsin
• Multifunctional Excipients (Co-processed Adjuvants)
• Synthetic Excipients
• Artificial Sweeteners
• Acesulfame-Potassium
• Aspartame
• Neotame
• Saccharin
• Sucralose
• Povidone
• Mineral Hydrocarbons
• Petrolatum
• Mineral Waxes
• Mineral Oils
• Colorants
• EDTA
• Flavors
• Glycine and Glycylglycine
• Vinyl Polymers
• Silicones
• Miscellaneous Synthetic Petrochemicals
• Oleochemicals
• Fatty Alcohols
• Glycerin
• Metal Stearate
• Others
• Natural Waxes
• Beeswax
• Candelilla Wax
• Carnauba Wax
• Cocoa and Shea Butters
• Lanolin
• Others
• Aroma agents
• Binders
• Buffers
• Chelating agents
• Glidants
• Humectants
• Lubricants
• Plasticizers
• Thickeners

VI. Company Profiles

• BASF Corporation
• Baxter Healthcare Corporation
• Chr Hansen
• Colorcon
• Cargill
• Degussa Corporation Rohm Pharma
• Dow Chemical Company
• Eastman Chemical Company
• FMC Corporation
• Fuji Chemical Industries
• Gattefosse Corporation
• International Specialty Products (ISP)
• JRS Pharma LP
• Mallinckrodt Group, Inc.
• Mutchler, Inc. Pharmaceutical Ingredients
• National Starch & Chemical Company
• Noviant, Inc
• Particle Dynamics
• Purac America
• Pharmaceutical Sourcing Group Americas (Janssen)
• Rhodia, Inc.
• Roquette America, Inc.
• Ruger Chemical Company
• SPI Pharma
• TIC Gums
• Tomita Pharmaceuticals
• Univar Company
• Wright Chemical Company