US Markets for Minimally Invasive Spinal Fusion Technologies 2007

Table of Contents

TABLE OF CONTENTS

LIST OF EXHIBITS

EXECUTIVE SUMMARY

METHODOLOGY

1.0 MINIMALLY INVASIVE SPINAL FUSION DEVICE OVERVIEW

• 1.1 Anatomy of the Human Spine
  • 1.1.1 Degenerative Spinal Disorders
  • 1.1.2 Deformity Spinal Disorders
  • 1.1.3 Trauma/Tumor Spinal Disorders
  • 1.1.4 Treatment Options
  • 1.1.5 Spinal Fusion
• 1.2 Thoracolumbar Fusion Devices
  • 1.2.1 Implant Design
  • 1.2.2 Thoracolumbar Pathology
• 1.3 Interbody Fusion Devices
  • 1.3.1 Implant Design
  • 1.3.2 Implant Material
  • 1.3.3 Surgical Approach
  • 1.3.4 Note on Interbody Fusion Device Classification

2.0 MINIMALLY INVASIVE SPINAL FUSION MARKET OVERVIEW

• 2.1 Market Overview
• 2.2 Minimally Invasive Spinal Fusion Definitions
• 2.3 Minimally Invasive Spinal Fusion Market Analysis
  • 2.3.1 Procedures
  • 2.3.2 Market Forecast
  • 2.3.3 Market Drivers and Limiters
• 2.4 Competitive Analysis
  • 2.4.1 Leading Competitors
  • 2.4.2 Other/Emerging Competitors

3.0 MINIMALLY INVASIVE TRADITIONAL THORACOLUMBAR IMPLANT MARKET

• 3.1 Market Overview
• 3.2 Market Analysis

4.0 MINIMALLY INVASIVE INTERBODY DEVICE MARKET

• 4.1 Market Overview
• 4.2 Market Analysis
  • 4.2.1 Procedures
  • 4.2.2 Market Forecast
    • 4.2.2.1 By Type
    • 4.2.2.2 By Approach

5.0 MINIMALLY INVASIVE ACCESS INSTRUMENTATION MARKET

• 5.1 Market Overview
• 5.2 Market Analysis

APPENDIX A: MRG ACRONYMS AND INITIALISMS

List of Exhibits

EXECUTIVE SUM MARY

• Exhibit ES-1: MI Spinal Fusion Market, by Segment, US (US$), 2005-2011
• Exhibit ES-2: MI Traditional Thoracolumbar Implant Market, US (US$), 2006 and 2011
• Exhibit ES-3: MI IBD Fusion Procedures, by Approach, US, 2005-2011
• Exhibit ES-4: MI Access Instrumentation Market, US (US$), 2005-2011
• Exhibit ES-5: Leading Competitors in the US MI Spinal Fusion Market, US, 2006

CHAPTER 1: MINIMALLY INVASIVE SPINAL FUSION DEVICE OVERVIEW

• Exhibit 1-1: Roles of the Spinal Column
• Exhibit 1-2: Instrumented Spinal Fusion Procedure Classification
• Exhibit 1-3: IBD Classification

CHAPTER 2: MINIMALLY INVASIVE SPINAL FUSION MARKET OVERVIEW

• Exhibit 2-1: MI Spine Fusion Market, by Device, US (US$) 2005-2011(Graphical Format)
• Exhibit 2-2: Procedural Definitions
• Exhibit 2-3: Market Value Definitions
• Exhibit 2-4: MI TL Spinal Fusion Procedures, US, 2005-2011
• Exhibit 2-5: MI Spinal Fusion Market, by Device, US (US$), 2005-2011 (Tabular Format)
• Exhibit 2-6: Drivers of the MI Spinal Fusion Market, US
• Exhibit 2-7: Limiters of the MI Spinal Fusion Market, US
• Exhibit 2-8: Leading Competitors in the MI Spinal Fusion Market, US, 2006
• Exhibit 2-9: Select Minimally Invasive Spine Products, US, 2006
• Exhibit 2-9: Select Minimally Invasive Spine Products, US, 2006 (cont.)
• Exhibit 2-9: Select Minimally Invasive Spine Products, US, 2006 (cont.)
• Exhibit 2-9: Select Minimally Invasive Spine Products, US, 2006 (cont.)

CHAPTER 3: MINIMALLY INVASIVE TRADITIONAL THORACOLUMBAR IMPLANT MARKET

• Exhibit 3-1: MI TL Implant Market, US (US$), 2005-2011 (Graphical Format)
• Exhibit 3-2: MI TL Implant Market, US (US$), 2005-2011 (Tabular Format)
• Exhibit 3-3: TL Implant ASPs per Procedure, by Surgery Type, US (US$), 2005-2011
• Exhibit 3-4: MI TL Implant System ASPs per Procedure, by Number of Levels, US, 2005-2011

CHAPTER 4: MINIMALLY INVASIVE INTERBODY DEVICE MARKET

• Exhibit 4-1: MI IBD Market, by Approach, as a % of Total, US (US$), 2005-2011
• Exhibit 4-2: MI IBD Spinal Fusion Procedures, US, 2005-2011
• Exhibit 4-3: MI IBD Spinal Fusion Procedures, by Approach, US, 2005-2011
• Exhibit 4-4: MI IBD Spinal Fusion Procedures, by Approach and Type, US, 2005-2011
• Exhibit 4-5: MI Interbody Spinal Fusion Procedures, by Approach and Type, as a % of Total, US, 2005-2011
• Exhibit 4-6: MI IBD Market, by Type and by Approach, US (US$), 2005-2011
• Exhibit 4-7: MI IBD Market Growth, by Type and by Approach, US, 2006-2011
• Exhibit 4-8: MI TLIF IBD Market, by Type, US (US$), 2005-2011
• Exhibit 4-9: MI PLIF IBD Market, by Type, US (US$), 2005-2011
• Exhibit 4-10: MI LLIF IBD Market, by Type, US (US$), 2005-2011
• Exhibit 4-11: MI ALIF IBD Market, by Type, US (US$), 2005-2011
• Exhibit 4-12: MI IBD Units per Procedure, by Type and Number of Levels, US, 2005-2011

CHAPTER 5: MINIMALLY INVASIVE ACCESS INSTRUMENTATION MARKET

• Exhibit 5-1: MI Spinal Fusion Access Instrumentation Market, US (US$), 2005-2011 (Graphical Format)
• Exhibit 5-2: MI Spinal Fusion Access Instrumentation Market, US (US$), 2005-2011 (Tabular Format)
• Exhibit 5-3: MI Spinal Fusion Access Instrumentation Systems, ASP per Procedure, US, 2005-2011