US Markets for Stem Cell Therapies 2008

Table of Contents

TABLE OF CONTENTS

LIST OF EXHIBITS

EXECUTIVE SUMMARY

METHODOLOGY

1.0 STEM CELL THERAPIES BACKGROUND

• 1.1 Regenerative Medicine
• 1.2 Stem Cell Sources, Properties, and Types
  • 1.2.1 Types of Germ Layers
  • 1.2.2 Properties of Stem Cells
  • 1.2.3 Sources and Types of Stem Cells
  • 1.2.4 Approaches to Stem Cell Therapy
  • 1.2.5 Stem Cell Dose
  • 1.2.6 Stem Cell Administration
• 1.3 Stem Cell Challenges
  • 1.3.1 History of Stem Cell Research
  • 1.3.2 Ethical Challenges
  • 1.3.3 Political Challenges
  • 1.3.4 Regulatory Challenges
  • 1.3.5 The Promise of Stem Cell Research
• 1.4 Stem Cell Market

2.0 US STEM CELL THERAPIES MARKET

• 2.1 Market Overview
• 2.2 Market Analysis
  • 2.2.1 Procedures
  • 2.2.2 Market Forecast
  • 2.2.3 Market Drivers and Limiters
    • 2.2.3.1 Market Drivers
    • 2.2.3.2 Market Limiters
• 2.3 Competitive Analysis

3.0 ORTHOPEDIC STEM CELL THERAPY MARKET

• 3.1 Market Overview
  • 3.1.1 Relevant Conditions
  • 3.1.2 Existing Therapies
  • 3.1.3 Stem Cell Therapies
• 3.2 Market Analysis
  • 3.2.1 Procedures
  • 3.2.2 Market Forecast
  • 3.2.3 Market Drivers and Limiters
• 3.3 Competitive Analysis

4.0 CARDIOVASCULAR STEM CELL THERAPY MARKET

• 4.1 Market Overview
  • 4.1.1 Relevant Conditions
  • 4.1.2 Existing Therapies
  • 4.1.3 Stem Cell Therapies
• 4.2 Market Analysis
  • 4.2.1 Procedures
  • 4.2.2 Market Forecast
  • 4.2.3 Market Drivers and Limiters
• 4.3 Competitive Analysis

5.0 DIABETES STEM CELL THERAPY MARKET

• 5.1 Market Overview
  • 5.1.1 Relevant Conditions
  • 5.1.2 Existing Therapies
  • 5.1.3 Stem Cell Therapies
• 5.2 Market Analysis
  • 5.2.1 Procedures
  • 5.2.2 Market Forecast
  • 5.2.3 Market Drivers and Limiters
• 5.3 Competitive Analysis

6.0 NEUROLOGICAL STEM CELL THERAPY MARKET

• 6.1 Market Overview
  • 6.1.1 Relevant Conditions
  • 6.1.2 Existing Therapies
  • 6.1.3 Stem Cell Therapies
• 6.2 Market Analysis
  • 6.2.1 Procedures
  • 6.2.2 Market Forecast
  • 6.2.3 Market Drivers and Limiters
• 6.3 Competitive Analysis

7.0 TISSUE AND ORGAN STEM CELL THERAPY MARKET

• 7.1 Market Overview
  • 7.1.1 Relevant Conditions
  • 7.1.2 Existing Therapies
  • 7.1.3 Stem Cell Therapies
• 7.2 Market Analysis
• 7.3 Competitive Analysis

8.0 COMPANY PROFILES

• 8.1 Aastrom Biosciences
• 8.2 Advanced Cell Technologies
• 8.3 Arteriocyte
• 8.4 Blackstone Medical
• 8.5 Cytori Therapeutics
• 8.6 Geron
• 8.7 Harvest Technologies
• 8.8 International Stem Cell Corporation
• 8.9 Osiris Therapeutics

List of Exhibits

EXECUTIVE SUMMARY

• Exhibit 1: Number of Stem Cell Therapy Products, US, 2007?2017
• Exhibit 2: Number of Orthopedic Stem Cell Therapy Products, US, 2007?2017
• Exhibit 3: Number of Cardiovascular Stem Cell Therapy Products, US, 2007?2017
• Exhibit 4: Number of Diabetes Stem Cell Therapy Products, US, 2007?2017
• Exhibit 5: Number of Neurological Stem Cell Therapy Products, US, 2007?2017
• Exhibit 6: Number of Tissue and Organ Stem Cell Therapy Products, US, 2007?2017

METHODOLOGY

CHAPTER 1: STEM CELL THERAPIES BACKGROUND

• Exhibit 7: The Differentiation Potential of Stem Cells
• Exhibit 8: The Ectoderm, Mesoderm and Endoderm Germ Layers
• Exhibit 9: The Balance of Stem Cell Self�]Renewal and Differentiation
• Exhibit 10: Cell Types Involved in Stem Cell Therapies
• Exhibit 11: Comparison of Types of Stem Cells
• Exhibit 12: Sources of Adult Stem Cells
• Exhibit 13: The US FDA Approval Process for Biopharmaceuticals

CHAPTER 2: US STEM CELL THERAPIES MARKET

• Exhibit 14: Number of Stem Cell Products in the Stem Cell Therapy Market, US, 2006?2017 (Graphical Format)
• Exhibit 15: Number of Stem Cell Products in the Stem Cell Therapy Market, US, 2006?2017 (Tabular Format)
• Exhibit 16: Drivers and Limiters of the Stem Cell Therapy Market, US
• Exhibit 17: Selected Companies in the Stem Cell Market, by Segment, US, 2007
• Exhibit 18: Selected Companies in the Stem Cell Market, by Technology. US, 2007
• Exhibit 19: Selected Companies in the Stem Cell Market, by Stem Cell Type
• Exhibit 20: Selected Companies in the Stem Cell Market, US, 2007

CHAPTER 3: ORTHOPEDIC STEM CELL THERAPY MARKET

• Exhibit 21: Orthopedic Stem Cell Therapy Market, US (US$) 2006?2012
• Exhibit 22: Number of Stem Cell Products in the Orthopedic Stem Cell Therapy Market, US, 2006?2017 (Graphical Format)
• Exhibit 23: Orthopedic Stem Cell Therapy Procedures, US, 2006?2012
• Exhibit 24: Total Orthopedic Incidence and Orthopedic Stem Cell Therapy Procedures, US, 2006?2017 (Graphical Format)
• Exhibit 25: Total Orthopedic Incidence and Orthopedic Stem Cell Therapy Procedures, US, 2006?2017 (Tabular Format)
• Exhibit 26: Number of Stem Cell Products in the Orthopedic Stem Cell Therapy Market, US, 2006?2017 (Tabular Format)
• Exhibit 27: Orthopedic Stem Cell Therapy Market, US (US$), 2006?2012 (Tabular Format)
• Exhibit 28: Drivers of the Orthopedic Stem Cell Therapy Market, US
• Exhibit 29: Limiters of the Orthopedic Stem Cell Therapy Market, US
• Exhibit 30: Selected Companies Offering and/or Developing Products in the Orthopedic Stem Cell Therapy Market, 2007

CHAPTER 4: CARDIOVASCULAR STEM CELL THERAPY MARKET

• Exhibit 31: Number of Stem Cell Products in the Cardiovascular Stem Cell Therapy Market, US, 2006?2017 (Graphical Format)
• Exhibit 32: Total Cardiovascular Procedures and Cardiovascular Stem Cell Therapy Procedures (Optimistic Scenario), US, 2006?2017 (Graphical Format)
• Exhibit 33: Total Cardiovascular Procedures and Cardiovascular Stem Cell Therapy Procedures (Optimistic Scenario), US, 2006?2017 (Tabular Format)
• Exhibit 34: Total Cardiovascular Procedures and Cardiovascular Stem Cell Therapy Procedures (Pessimistic Scenario), US, 2006?2017 (Graphical Format)
• Exhibit 35: Total Cardiovascular Procedures and Cardiovascular Stem Cell Therapy Procedures (Pessimistic Scenario), US, 2006?2017 (Tabular Format)
• Exhibit 36: Number of Stem Cell Products in the Cardiovascular Stem Cell Therapy Market, US, 2006?2017 (Tabular Format)
• Exhibit 37: Drivers of the Cardiovascular Stem Cell Therapy Market, US
• Exhibit 38: Limiters of the Cardiovascular Stem Cell Therapy Market, US
• Exhibit 39: Selected Companies Developing Products in the Cardiovascular Stem Cell Therapy Market, 2007

CHAPTER 5: DIABETES STEM CELL THERAPY MARKET

• Exhibit 40: Number of Stem Cell Products in the Diabetes Stem Cell Therapy Market, US, 2006?2017 (Graphical Format)
• Exhibit 41: Total Diabetes Procedures and Diabetes Stem Cell Therapy Procedures (Optimistic Scenario), US, 2006?2017 (Graphical Format)
• Exhibit 42: Total Diabetes Procedures and Diabetes Stem Cell Therapy Procedures (Optimistic Scenario), US, 2006?2017 (Tabular Format)
• Exhibit 43: Total Diabetes Procedures and Diabetes Stem Cell Therapy Procedures (Pessimistic Scenario), US, 2006?2017 (Graphical Format)
• Exhibit 44: Total Diabetes Procedures and Diabetes Stem Cell Therapy Procedures (Pessimistic Scenario), US, 2006?2017 (Tabular Format)
• Exhibit 45: Number of Stem Cell Products in the Diabetes Stem Cell Therapy Market, US, 2006?2017 (Tabular Format)
• Exhibit 46: Drivers of the Diabetes Stem Cell Therapy Market, US
• Exhibit 47: Limiters of the Diabetes Stem Cell Therapy Market, US
• Exhibit 48: Selected Companies Developing Products in the Diabetes Stem Cell Therapy Market, 2007

CHAPTER 6: NEUROLOGICAL STEM CELL THERAPY MARKET

• Exhibit 49: Number of Stem Cell Products in the Neurological Stem Cell Therapy Market, US, 2006?2017 (Graphical Format)
• Exhibit 50: Total Neurological Procedures and Neurological Stem Cell Therapy Procedures (Optimistic Scenario), US, 2006?2017 (Graphical Format)
• Exhibit 51: Total Neurological Procedures and Neurological Stem Cell Therapy Procedures (Optimistic Scenario), US, 2006?2017 (Tabular Format)
• Exhibit 52: Total Neurological Procedures and Neurological Stem Cell Therapy Procedures (Pessimistic Scenario), US, 2006?2017 (Graphical Format)
• Exhibit 53: Total Neurological Procedures and Neurological Stem Cell Therapy Procedures (Pessimistic Scenario), US, 2006?2017 (Tabular Format)
• Exhibit 54: Number of Stem Cell Products in the Neurological Stem Cell Therapy Market, US, 2006?2017 (Tabular Format)
• Exhibit 55: Drivers of the Neurological Stem Cell Therapy Market, US
• Exhibit 56: Limiters of the Neurological Stem Cell Therapy Market, US
• Exhibit 57: Selected Companies Developing Products in the Neurological Stem Cell Therapy Market, US, 2007

CHAPTER 7: TISSUE AND ORGAN STEM CELL THERAPY MARKET

• Exhibit 58: Number of Stem Cell Products in the Tissue and Organ Stem Cell Therapy Market, US, 2006?2017 (Graphical Format)
• Exhibit 59: Number of Stem Cell Products in the Tissue and Organ Stem Cell Therapy Market, US, 2006?2017 (Tabular Format)
• Exhibit 60: Selected Companies Developing Products in the Tissue and Organ Stem Cell Therapy Market, US, 2007

CHAPTER 8: COMPANY PROFILES