Emerging Technologies for the Diagnosis and Treatment of Coronary Artery Disease 2007

Table of Contents

TABLE OF CONTENTS

LIST OF EXHIBITS

EXECUTIVE SUMMARY

METHODOLOGY

1.0 CORONARY ARTERY DISEASE

• 1.1 Introduction
• 1.2 An Overview of Coronary Artery Disease
• 1.3 Epidemiology
• 1.4 Existing Diagnosis and Treatment Options for Coronary Artery Disease
  • 1.4.1 Diagnosis
  • 1.4.2 Treatment
• 1.5 Future Outlook

2.0 DIAGNOSTIC IMAGING DEVICES

• 2.1 Overview
• 2.2 Intravascular Ultrasound
  • 2.2.1 Technology Overview
  • 2.2.2 Market Potential
  • 2.2.3 Competitor Insights
• 2.3 Vulnerable Plaque Diagnosis
  • 2.3.1 Technology Overview
    • 2.3.1.1 Computed Tomography
    • 2.3.1.2 Magnetic Resonance Imaging
    • 2.3.1.3 Near-Infrared Spectroscopy
    • 2.3.1.4 Optical Coherence Tomography
    • 2.3.1.5 Thermography
  • 2.3.2 Market Potential
  • 2.3.3 Competitor Insights
    • 2.3.3.1 Computed Tomography
    • 2.3.3.2 Magnetic Resonance Imaging
    • 2.3.3.3 Near-Infrared Spectroscopy
    • 2.3.3.4 Optical Coherence Tomography
    • 2.3.3.5 Thermography

3.0 REVASCULARIZATION DEVICES

• 3.1 Overview
• 3.2 Novel Stent Technologies
  • 3.2.1 Technology Overview
    • 3.2.1.1 Bioabsorbable Stents
    • 3.2.1.2 Specially Coated Drug-Eluting Stents
  • 3.2.2 Market Potential
    • 3.2.2.1 Bioabsorbable Stents
    • 3.2.2.2 Specially Coated Drug-Eluting Stents
    • 3.2.2.3 Overall Coronary Stent Market
  • 3.2.3 Competitor Insights
    • 3.2.3.1 Bioabsorbable Stents
    • 3.2.3.2 Specially Coated Drug-Eluting Stents
• 3.3 Synthetic Grafts
  • 3.3.1 Technology Overview
  • 3.3.2 Market Potential
  • 3.3.3 Competitor Insights
• 3.4 Remote Navigation Technologies
  • 3.4.1 Technology Overview
  • 3.4.2 Market Potential
  • 3.4.3 Competitor Insights

4.0 NEOVASCULARIZATION THERAPIES

• 4.1 Overview
• 4.2 Therapeutic Angiogenesis
  • 4.2.1 Technology Overview
    • 4.2.1.1 Gene Therapy
    • 4.2.1.2 Stem Cell Therapy
  • 4.2.2 Market Potential
  • 4.2.3 Competitor Insights
    • 4.2.3.1 Gene Therapy
    • 4.2.3.2 Stem Cell Therapy

APPENDIX A: MRG ACRONYMS AND INITIALISMS

APPENDIX B: ADDITIONAL COMPETITOR INFORMATION

List of Exhibits

EXECUTIVE SUMMARY

• Exhibit 1: New Imaging Technology Procedures, US, 2009-2018
• Exhibit 2: PCIs, by Type, US, 2018
• Exhibit 3: Therapeutic Angiogenesis Procedures, US, 2013-2018

CHAPTER 1: CORONARY ARTERY DISEASE

• Exhibit 4: Frequently Used CAD Terminology
• Exhibit 5: Stages of Lesion Development
• Exhibit 6: Common CAD Risk Factors
• Exhibit 7: Global Life Expectancy, 2006
• Exhibit 8: CAD Incidence, by Region, 2007-2013 (Tabular Format)
• Exhibit 9: Symptoms of CAD
• Exhibit 10: CAD Treatment Options

CHAPTER 2: DIAGNOSTIC IMAGING DEVICES

• Exhibit 11: IVUS Procedures, by Region, 2006-2011
• Exhibit 12: New Imaging Technology Penetration, as a % of Total, US, 2009-2018
• Exhibit 13: New Imaging Technology Penetration, US, 2009-2018

CHAPTER 3: REVASCULARIZATION DEVICES

• Exhibit 14: BAS Procedures, US, 2012-2018
• Exhibit 15: BAS Penetration, US, 2012-2018
• Exhibit 16: SCDES Procedures, US, 2010-2018
• Exhibit 17: SCDES Penetration, US, 2010-2018
• Exhibit 18: PCIs, by Type, as a % of Total, US, 2008-2018
• Exhibit 19: PCIs, by Type, US, 2008-2018
• Exhibit 20: PCI Growth, by Type, US, 2008-2018
• Exhibit 21: BAS in Development, 2007
• Exhibit 22: BAS Material Absorption Time
• Exhibit 23: Polymer-Free and Bioabsorbable Polymer-Coated Stents, 2007
• Exhibit 24: Synthetic Graft Procedures, 2011-2018
• Exhibit 25: Synthetic Graft Penetration, 2011-2018
• Exhibit 26: RNT Procedures, 2008-2018
• Exhibit 27: RNT Penetration, US, 2008-2018

CHAPTER 4: NEOVASCULARIZATION THERAPIES

• Exhibit 28: Therapeutic Angiogenesis Procedures, US, 2013-2018
• Exhibit 29: Therapeutic Angiogenesis Procedure Penetration, US, 2013-2018

APPENDIX A: MRG ACRONYMS AND INITIALISMS

APPENDIX B: ADDITIONAL COMPETITOR INFORMATION