Arthritis - US - June 2007

Table of Contents

• Scope and Themes
• What you need to know
• Definition
• Data for this report
• Abbreviations and terms
• Abbreviations
• Terms
• Executive Summary
• Arthritis: not one disease, but over a hundred
• ABCs of arthritis and other musculoskeletal maladies
• Widespread disease
• Causes are not always known
• Treatments/therapies/activities/procedures
• Increasing prevalence
• Advertising to the growing population of people with arthritis
• Background
• Introduction: types of arthritis
• Osteoarthritis (OA)
• Fibromyalgia
• Rheumatoid arthritis (RA)
• Other types of arthritis
• Other musculoskeletal disorders
• Repetitive motion disorders (RMDs)
• Common symptoms of musculoskeletal disorders
• Inflammation
• Debilitation
• Fatigue
• Negative impact on emotional well-being
• Specific functional limitations
• The range of experience
• Prevalence and Extent of Suffering
• Introduction
  • Figure 1: Arthritis prevalence among adults, by age and gender, 2007
• Costs of treating arthritis are a growing concern
• Prevalence of severe OA, RA, chronic pain, and backache
  • Figure 2: Prevalence of OA, RA, chronic pain, and backache, by gender, January-October 2006
  • Figure 3: Prevalence of OA, RA, chronic pain, and backache, by age, January-October 2006
  • Figure 4: Prevalence of OA, RA, chronic pain, and backache, by race/ethnicity, January-October 2006
• Ailment severity
  • Figure 5: Severity of OA, RA, chronic pain, and backache ailments, by gender and age, January-October 2006
• Prevalence of arthritis: diagnosed vs. undiagnosed
  • Figure 6: Prevalence of arthritis and concern about contracting arthritis, by age, April 2007
  • Figure 7: Prevalence of arthritis and concern about contracting arthritis, by race/ethnicity, April 2007
• Prevalence of specific types of arthritis
  • Figure 8: Prevalence of specific arthritis types within the arthritic population, by gender and age, April 2007
• Prevalence of non-arthritis musculoskeletal disorders
  • Figure 9: Prevalence of specific musculoskeletal disorders not including arthritis, by age, April 2007
• Anatomical site of arthritis
  • Figure 10: Anatomical site of arthritis, by gender, April 2007
  • Figure 11: Anatomical site of arthritis, by age, April 2007
• Causes and Prevention
• Introduction
• Causes
• Osteoarthritis (OA)
• Fibromyalgia
• Rheumatoid arthritis (RA)
• Other types of arthritis
• Other musculoskeletal disorders
• RMDs
• Prevention
• Osteoarthritis
• Fibromyalgia
• Rheumatoid arthritis
• Other types of arthritis
• Other musculoskeletal disorders
• RMDs
• Prescription and OTC Medication
• Introduction
• Top-selling arthritis drugs
  • Figure 12: Global sales of top-selling arthritis drugs, 2004 and 2005
  • Figure 13: Top-selling arthritis drugs, by use, positive and negative impact
• New OTC medications and brand extensions
  • Figure 14: Pain reliever new product launches, 2001-07
• Topical pain relievers
  • Figure 15: Advanced Healthcare Distributors Muscle & Joint Cream
  • Figure 16: Activ On Topical Analgesic Ultra Strength Joint & Muscle Pain Relief
  • Figure 17: Procter & Gamble Thermacare HeatWraps
  • Figure 18: WellPatch Arthritis Pain Releiving Pads
  • Figure 19: EMU Lifestyles Arthritic Joint Creme
• Easy to open bottles
  • Figure 20: CVS Pharmacy Arthritis Pain Relief Caplets
  • Figure 21: Bayer Healthcare Aleve Arthritis Relief Tablets
  • Figure 22: Tylenol Arthritis Pain EZ-Open Cap
• Long-lasting formulas
  • Figure 23: Equate Arthritis Pain Relief caplets
• Enteric coated aspirin
  • Figure 24: Ecotrin Aspirin Arthritis Strength
• Use of prescription vs. OTC medications
  • Figure 25: Use of prescription and OTC medications to treat OA, RA, chronic pain, and backache, by gender, January-October 2006
• OTC products gain sales as Vioxx and Bextra are pulled from the market
• Reasons for not taking prescription medication
  • Figure 26: Reasons for not taking prescription medications, by age, April 2007
• Reasons for not taking OTC medication
  • Figure 27: Reason for not taking OTC remedies, by gender, April 2007
  • Figure 28: Reasons for not taking OTC remedies, by age, April 2007
• Use of pain relieving liquids, rubs, and wraps among OA, RA, chronic pain, and backache sufferers
  • Figure 29: Use of pain relieving liquids, rubs, or wraps to treat OA, RA, chronic pain, and backache, January-October 2006
• Advertising Medications to Those with Arthritis
• Introduction
• NSAID TV ADS
• Aleve
  • Figure 30: Television spot: Aleve pain reliever
  • Figure 31: Television spot: Aleve pain reliever
  • Figure 32: Television spot: Aleve pain reliever
• ANALGESIC TV ADS
• Capzasin
  • Figure 33: Television spot: Capzasin topical pain reliever
• WellPatch
  • Figure 34: Television spot: WellPatch
• Tylenol Arthritis Pain
  • Figure 35: Television spot: Tylenol Arthritis Pain
• TNF-a INHIBITOR TV ADS
• Enbrel
  • Figure 36: Television spot: Enbrel
  • Figure 37: Television spot: Two Futures
• Humira
  • Figure 38: Television spot: Humira
• Herbal Remedies and Dietary Supplements
• Introduction
• Bovine cartilage
• Bromelain
• Chondroitin sulfate
• Devil' s claw
• Feverfew
• Fish oil
• Flaxseed and flaxseed oil
• Ginger
• GLA (gamma-linolenic acid)
• Glucosamine
• Gotu kola, gotu cola, brahmi, brahmi-buti, Indian pennywort
• Green tea or Chinese tea
• Marijuana and cannabis-based medicine
• Shark cartilage
• Turmeric
• Type II chicken collagen, chicken collagen, chicken type II collagen, type II collagen
• White willow, willow bark, white willow bark
• Reasons for not taking herbal remedies
  • Figure 39: Reasons for not taking herbal remedies, prescription medication or otc medication, April 2007
• Treatment Via Services and Activities
• Services
• Arthritis therapy
• Pain and stress management
• Aquatic therapy/hydrotherapy
• Environmental assessment
• Nutrition management
• Activities
• Yoga
• Health clubs
• Swimming
• Bicycling
• Walking/jogging
• Tai Chi
• Temperature therapy
• Comparison of popularity of treatments including prescription, OTC, herbal, and services
  • Figure 40: Treatments used, April 2007
  • Figure 41: Treatments used by those with diangosed arthritis, April 2007
• Role of the Medical Community
  • Figure 42: Visits to medical practicioners in past 12 months, by condition, January-October 2006
• Primary care doctor/general practitioner (GP)
• Rheumatologist
• Orthopedist/orthopedic surgeon
• Surgery
• OA surgeries
• RA surgeries
• Fibromyalgia surgery
• Other surgeries and procedures
  • Figure 43: Television spot: Synvisc joint fluid treatment--surgery alternative
• RMD surgery
• Osteopath
• Physical therapist
• Chiropractor
• Massage therapist
• Acupuncturist
• Attitudes towards healthcare professionals
  • Figure 44: Attitudes toward healthcare professionals, by condition, January-October 2006
• Access to healthcare professionals
  • Figure 45: Lack of medical insurance, by condition, January-October 2006
• Future Trends
• Population of arthritics to grow by four million in next seven years
  • Figure 46: Prevalence of adult arthritis, by gender and age, 2012
• New treatments
• Gene therapy
• Vaccines
• Biologics
• Trial phase drugs
• RA treatments
• Vioxx replacements
• Alternative remedies
• FDA requires supplement testing for purity
• Early diagnosis
• Appendix: Classes of Medication for Treating Arthritis
• NSAIDS
• Traditional NSAIDS
• Description and uses
• Side effects
• COX-2 inhibitors
• Description and uses
• Side effects
• Salicylates
• Description and uses
• Side effects
• Analgesics
• Description and uses
• Side effects
• Disease-Modifying-Anti-Rheumatic Drugs (DMARDs)
• Description and uses
• Side effects
• Biologic response modifiers
• TNF-a inhibitors
• Description and uses
• Side effects
• Selective B-cell inhibitor
• Description and uses
• Side effects
• IL-1 inhibitor
• Description and uses
• Side effects
• Selective costimulation modulator
• Description and uses
• Side effects
• Corticosteroids
• Description and uses
• Side effects
• Fibromyalgia drugs
• Description and uses
• Side effects
• Gout drugs
• Description and uses
• Side effects
• Appendix: Trade Associations