U.S. Market for Bone Morphogenic Proteins in Orthopaedics

Table of Contents

Chapter 1 Introduction

• Bone Grafting
• Biological Activity of Bone Grafts
• Current Bone Graft Technologies and Applications
• Autografts
  • Advantages of Autografts
  • Limitation of Autografts
• Machined Allografts
  • Advantages and Limitations of Machined Allografts
• Synthetic Bone Graft Substitutes
• Advantages and Limitations of Synthetic Bone Graft Substitutes
• Demineralised Bone Matrix
• Advantages and Disadvantages of Demineralised Bone Matrices
• Bone Morphogenic Proteins
  • Advantages and Limitations of Bone Morphogenic Proteins
• Comparative Properties of Autografts and Allografts
• Comparative Properties of Synthetic and Cell-Based Bone Graft Substitutes

Chapter 2 Orthopaedic Procedures and Bone Graft Utilisation

• Bone Graft Utilisation in Orthopaedic Applications (U.S., 2004)
• Total Number of Spinal Fusion Procedures in U.S., 2004
• Total Number of Spinal Fusion Procedures by Selected Geographic Regions in the U.S., 2004
• Total Number of Spinal Fusion Procedures by Anatomy, U.S., 2004

Chapter 5 Bone Morphogenic Proteins (BMP) Market

• Market Drivers and Restraints
  • Market Opportunities
  • End-User Trends
  • Industry Challenges
    • Market Challenges
  • BMP Products
• rhBMP-2/ACS (marketed as InFUSE Graft in the U.S., and as InductOS in Europe)
  • History of rhBMP-2/ACS
  • Product Description
  • Development of rhBMP/ACS
  • Preclinical Studies
  • Clinical Studies
• Indications and Contradictions
• Development of InductOS in Europe
• OP-1
  • Development of OP-1
  • Product Description
  • Preclinical Studies
  • Clinical Studies
  • FDA Indications and Contradictions
• MP52
  • Product Description
  • History of Development
  • Preclinical and Clinical Studies
  • FDA Status
• Pricing Analysis
  • Pricing Forecasts for BMPs
• U.S. Market Size for BMPs
  • Revenue Analysis
• U.S. Unit Shipments of BMPs
  • Analysis of Unit Shipment of BMPs in the U.S.
• Surgeons Prospective