High-Content Screening for Target Identification and Validation

Table of Contents

1 | EXECUTIVE SUMMARY

• Scope and Methodology
  • 1. Scope
  • 2. Methodology
• Key Findings
  • 1. Introduction
  • 2. Noteworthy Emerging Technologies and Applications
  • 3. Assessment of Competing Technologies

2 | TECHNOLOGY AND APPLICATIONS VIEWPOINT

• Technology and Applications Analysis
  • 1. Technology Primer
  • 2. High Content Screening Vs. Competing Technologies
• Technological Developments and Innovations in Companies
  • 1. cellWorx High Content Screening Analysis System developed by Applied Precision--USA
  • 2. Microarray Platform developed by Metrigenics--USA
  • 3. Acumen Explorer 488 developed by TTP LabTech--USA
  • 4. Redistribution Technology by BioImage
• Technology Adoption Factor
  • 1. Analysis of Technology Drivers
  • 2. Analysis of Technology Challenges
  • 3. Analysis of Technology Restraints
• Future Trends; Capital Funding; Partnerships and Alliances
  • 1. Technology and Application Trends
  • 2. Capital Funding Analysis
  • 3. Partnerships and Alliances

3 | ASSESSMENT OF INNOVATIONS AND OPPORTUNITIES- USA

• Technological Developments and Innovations in Universities
  • 1. High-Throughput Screening of Neuraminidase Inhibitors--USA
  • 2. A Small Molecule that Induces Mitotic Arrest--USA

4 | ASSESSMENT OF INNOVATIONS AND OPPORTUNITIES- EUROPE AND ASIA PACIFIC

• Technological Developments and Innovations in Companies
  • 1. Multicolor Color BiFC Assays Developed by Purdue University--USA
  • 2. Electrochemical High-Content Screening of Nitric Oxide Release from Endothelial Cells--USA
  • 3. Cellenger- A High Content Screening Instrument developed by Definiens--Germany
  • 4. High-Content Screening Microscopy Identifies Novel Proteins--Germany
  • 5. Pathfinder Technology developed by IMSTAR
  • 6. Bionas Analyzing System
• Technological Developments and Innovations in Universities
  • 1. A High-throughput screening of Genes Encoding Proteins--Tokyo
  • 2. High-Content Screening Using a Human Kinase siRNA Library--Germany

5 | KEY PATENTS; CONTACTS; GLOSSARY

• Key Patents
  • 1. US Patents; 2006
  • 2. US Patents; 2005
• Contacts and Glossary
  • 1. Database of Key industry Participants
  • 2. University Participants
  • 3. Glossary

6 | FROST & SULLIVAN 2006 SCIENCE AND TECHNOLOGY AWARDS

• Product Innovation Award
  • 1. Award Description
  • 2. Award Recipient
• Technology Innovation Award
  • 1. Award Description
  • 2. Award Recipient
• Excellence in Technology
  • 1. Award Description
  • 2. Award Recipient

7 | DECISION SUPPORT DATABASE

• Database Tables
  • 1. Total Healthcare Expenditure (1999-2006)
  • 2. Pharma R&D Expenditure (1999-2006)
  • 3. Govt Biotech R&D Investment (1999-2006)
  • 4. Private Biotech R&D Investment (1999-2006)