Abstract
Microfluidics is a branch of physics and biotechnology, having emerged only in
the 1990' s that studies the behaviour of fluids at the microscale and
mesoscale.
Microfluidics is also defined operationally as dealing with micro machined
devices that process fluids at the micro-scale for performing single functions
or integrating multiple functions such as:
- Sample dilution
- Sample injection
- Sample and reagents metering
- Mixing, incubation and components separation
Microfluidics serves to miniaturize and integrate processes that were
previously done at larger scale in separate operations.
Miniaturization permits both increased speed of analysis as well as
minimization of sample and reagent consumption.
For example, using a microfluidic chip, a Sanger DNA sequencing run can be
completed in 30 minutes or less versus 2 hours or more by conventional
capillary electrophoresis.